Michael Dumas
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Explore the profile of Michael Dumas including associated specialties, affiliations and a list of published articles.
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19
Citations
529
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Recent Articles
1.
Grillo G, Boyarchuk E, Mihic S, Ivkovic I, Bertrand M, Jouneau A, et al.
Hum Mol Genet
. 2024 Nov;
34(2):161-177.
PMID: 39562305
Since its discovery as a causative gene of the Immunodeficiency with Centromeric instability and Facial anomalies syndrome, ZBTB24 has emerged as a key player in DNA methylation, immunity and development....
2.
Al Adhami H, Vallet J, Schaal C, Schumacher P, Bardet A, Dumas M, et al.
Nucleic Acids Res
. 2023 Feb;
51(7):3130-3149.
PMID: 36772830
In mammals, many germline genes are epigenetically repressed to prevent their illegitimate expression in somatic cells. To advance our understanding of the mechanisms restricting the expression of germline genes, we...
3.
Al Adhami H, Bardet A, Dumas M, Cleroux E, Guibert S, Fauque P, et al.
BMC Biol
. 2022 Mar;
20(1):70.
PMID: 35317801
Background: Cytosine DNA methylation is a heritable epigenetic mark present in most eukaryotic groups. While the patterns and functions of DNA methylation have been extensively studied in mouse and human,...
4.
Foray A, Candon S, Hildebrand S, Marquet C, Valette F, Pecquet C, et al.
Proc Natl Acad Sci U S A
. 2021 Nov;
118(47).
PMID: 34782469
Insulin-dependent or type 1 diabetes (T1D) is a polygenic autoimmune disease. In humans, more than 60 loci carrying common variants that confer disease susceptibility have been identified by genome-wide association...
5.
Dahlet T, Truss M, Frede U, Al Adhami H, Bardet A, Dumas M, et al.
Nat Commun
. 2021 Jun;
12(1):3582.
PMID: 34117224
In mouse development, long-term silencing by CpG island DNA methylation is specifically targeted to germline genes; however, the molecular mechanisms of this specificity remain unclear. Here, we demonstrate that the...
6.
Dumas M, Laugeman E, Sevak P, Snyder K, Mao W, Chetty I, et al.
J Appl Clin Med Phys
. 2020 Oct;
21(11):288-294.
PMID: 33044040
Purpose: To investigate the differences between internal target volumes (ITVs) contoured on the simulation 4DCT and daily 4DCBCT images for lung cancer patients treated with stereotactic body radiotherapy (SBRT) and...
7.
Dahlet T, Argueso Lleida A, Al Adhami H, Dumas M, Bender A, Ngondo R, et al.
Nat Commun
. 2020 Jun;
11(1):3153.
PMID: 32561758
Mouse embryos acquire global DNA methylation of their genome during implantation. However the exact roles of DNA methyltransferases (DNMTs) in embryos have not been studied comprehensively. Here we systematically analyze...
8.
Bruschi M, Garnier L, Cleroux E, Giordano A, Dumas M, Bardet A, et al.
Cancer Res
. 2020 Mar;
80(11):2101-2113.
PMID: 32213541
Colorectal cancer initiation and progression result from the accumulation of genetic and epigenetic alterations. Although aberrant gene expression and DNA methylation profiles are considered hallmarks of colorectal cancer development, the...
9.
Fonti C, Saumet A, Abi-Khalil A, Orsetti B, Cleroux E, Bender A, et al.
Int J Cancer
. 2019 May;
145(5):1299-1311.
PMID: 31093963
Molecular subtypes of breast cancer are defined on the basis of gene expression and genomic/epigenetic pattern differences. Different subtypes are thought to originate from distinct cell lineages, but the early...
10.
Seaberg D, Elseroad S, Dumas M, Mendiratta S, Whittle J, Hyatte C, et al.
Acad Emerg Med
. 2017 Aug;
24(11):1327-1333.
PMID: 28834070
Background: Emergency department (ED) superutilizers (patients with five or more visits/year) comprise only 5% of the patients seen yet comprise 25% of total ED visits. Although the reasons for this...