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Michael D Conkright

Explore the profile of Michael D Conkright including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 1813
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11.
Zhang X, Odom D, Koo S, Conkright M, Canettieri G, Best J, et al.
Proc Natl Acad Sci U S A . 2005 Mar; 102(12):4459-64. PMID: 15753290
Hormones and nutrients often induce genetic programs via signaling pathways that interface with gene-specific activators. Activation of the cAMP pathway, for example, stimulates cellular gene expression by means of the...
12.
Screaton R, Conkright M, Katoh Y, Best J, Canettieri G, Jeffries S, et al.
Cell . 2004 Sep; 119(1):61-74. PMID: 15454081
Elevations in circulating glucose and gut hormones during feeding promote pancreatic islet cell viability in part via the calcium- and cAMP-dependent activation of the transcription factor CREB. Here, we describe...
13.
Conkright M, Canettieri G, Screaton R, Guzman E, Miraglia L, Hogenesch J, et al.
Mol Cell . 2003 Oct; 12(2):413-23. PMID: 14536081
The cAMP responsive factor CREB stimulates gene expression, following its phosphorylation at Ser133, via recruitment of the coactivator CBP. In certain cell types, CREB also functions as a constitutive activator,...
14.
Conkright M, Guzman E, Flechner L, Su A, Hogenesch J, Montminy M
Mol Cell . 2003 Apr; 11(4):1101-8. PMID: 12718894
We have employed a hidden Markov model (HMM) based on known cAMP responsive elements to search for putative CREB target genes. The best scoring sites were positionally conserved between mouse...