Michael D Cole
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Explore the profile of Michael D Cole including associated specialties, affiliations and a list of published articles.
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61
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2530
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Recent Articles
1.
Yankova Y, Cole M, Cirstea S, Warren J
Forensic Sci Int
. 2024 Jun;
361:112103.
PMID: 38901059
In the forensic science context petrol is considered the most common fire accelerant. However, the identification and classification of petrol sources through the years has been proven to be a...
2.
Morrissey J, Stodter A, Sherratt F, Cole M
Sci Justice
. 2023 Jan;
63(1):74-82.
PMID: 36631184
This research discusses the development of academic-practitioner partnerships in forensic science and examines the opinions and experience of those involved in the field. An anonymous online survey was completed by...
3.
Hinds J, Feris E, Wilkins O, Deary L, Wang X, Cole M
PLoS One
. 2022 Aug;
17(8):e0272771.
PMID: 36018850
MYC is one of the most dysregulated oncogenes and is thought to be fundamental to tumor formation and/or maintenance in many cancer types. This dominant pro-tumor activity makes MYC an...
4.
Feris E, Hinds J, Cole M
Oncotarget
. 2021 Oct;
12(21):2147-2157.
PMID: 34676047
Mechanism-based targeted therapies have exhibited remarkable success in treating otherwise untreatable or unresectable cancers. Novel targeted therapies that correct dysregulated transcriptional programs in cancer are an unmet medical need. The...
5.
Musolf A, Simpson C, Moiz B, Pikielny C, Middlebrooks C, Mandal D, et al.
Cancer Res
. 2021 Apr;
81(12):3162-3173.
PMID: 33853833
Although lung cancer is known to be caused by environmental factors, it has also been shown to have genetic components, and the genetic etiology of lung cancer remains understudied. We...
6.
Feris E, Hinds J, Cole M
PLoS One
. 2019 Dec;
14(12):e0225784.
PMID: 31790487
Our primary goal is to therapeutically target the oncogenic transcription factor MYC to stop tumor growth and cancer progression. Here, we report aspects of the biophysical states of the MYC...
7.
Gorlov I, Pikielny C, Frost H, Her S, Cole M, Strohbehn S, et al.
BMC Bioinformatics
. 2018 Nov;
19(1):430.
PMID: 30453881
Background: Because driver mutations provide selective advantage to the mutant clone, they tend to occur at a higher frequency in tumor samples compared to selectively neutral (passenger) mutations. However, mutation...
8.
Grela A, Gautam L, Cole M
Forensic Sci Int
. 2018 Oct;
292:50-60.
PMID: 30292936
Drug-facilitated sexual assault (DFSA) is a sexual act in which the victim is unable to give or rescind consent due to intoxication with alcohol and/or drugs that have been self-administered...
9.
Weyburne E, Wilkins O, Sha Z, Williams D, Pletnev A, de Bruin G, et al.
Cell Chem Biol
. 2017 Jan;
24(2):218-230.
PMID: 28132893
The proteasome inhibitors carfilzomib (Cfz) and bortezomib (Btz) are used successfully to treat multiple myeloma, but have not shown clinical efficacy in solid tumors. Here we show that clinically achievable...
10.
HS3ST1 genotype regulates antithrombin's inflammomodulatory tone and associates with atherosclerosis
Smits N, Kobayashi T, Srivastava P, Skopelja S, Ivy J, Elwood D, et al.
Matrix Biol
. 2017 Jan;
63:69-90.
PMID: 28126521
The HS3ST1 gene controls endothelial cell production of HS - a form of heparan sulfate containing a specific pentasaccharide motif that binds the anticoagulant protein antithrombin (AT). HS has long...