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Michael Cipriano

Explore the profile of Michael Cipriano including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 348
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Recent Articles
1.
Sharma A, Cipriano M, Ferrins L, Hajduk S, Mensa-Wilmot K
iScience . 2022 Oct; 25(11):105302. PMID: 36304107
NEU-4438 is a lead for the development of drugs against , which causes human African trypanosomiasis. Optimized with phenotypic screening, targets of NEU-4438 are unknown. Herein, we present a cell...
2.
Garrison P, Khan U, Cipriano M, Bush P, McDonald J, Sur A, et al.
mBio . 2021 Jul; 12(4):e0172521. PMID: 34311578
African trypanosomes utilize glycosylphosphatidylinositol (GPI)-anchored variant surface glycoprotein (VSG) to evade the host immune system. VSG turnover is thought to be mediated via cleavage of the GPI anchor by endogenous...
3.
Ndyabawe K, Cipriano M, Zhao W, Haidekker M, Yao K, Mao L, et al.
ACS Biomater Sci Eng . 2020 Dec; 7(1):350-359. PMID: 33320530
Animal models are frequently used in drug discovery because they represent a mammalian in vivo model system, they are the closest approximation to the human brain, and experimentation in humans...
4.
Suarez C, Lentini G, Ramaswamy R, Maynadier M, Aquilini E, Berry-Sterkers L, et al.
Nat Commun . 2019 Sep; 10(1):4041. PMID: 31492901
Members of the Apicomplexa phylum, including Plasmodium and Toxoplasma, have two types of secretory organelles (micronemes and rhoptries) whose sequential release is essential for invasion and the intracellular lifestyle of...
5.
Fritz-Laylin L, Prochnik S, Ginger M, Dacks J, Carpenter M, Field M, et al.
Cell . 2010 Mar; 140(5):631-42. PMID: 20211133
Genome sequences of diverse free-living protists are essential for understanding eukaryotic evolution and molecular and cell biology. The free-living amoeboflagellate Naegleria gruberi belongs to a varied and ubiquitous protist clade...
6.
Ochsenreiter T, Cipriano M, Hajduk S
PLoS One . 2008 Feb; 3(2):e1566. PMID: 18270563
The editing of trypanosome mitochondrial mRNAs produces transcripts necessary for mitochondrial functions including electron transport and oxidative phosphorylation. Precursor-mRNAs are often extensively edited by specific uridine insertion or deletion that...
7.
Gu S, Anderson I, Kunin V, Cipriano M, Minovitsky S, Weber G, et al.
Bioinformatics . 2007 Jan; 23(6):764-6. PMID: 17234642
Unlabelled: We describe a general multiplatform exploratory tool called TreeQ-Vista, designed for presenting functional annotations in a phylogenetic context. Traits, such as phenotypic and genomic properties, are interactively queried from...
8.
Ochsenreiter T, Cipriano M, Hajduk S
RNA . 2006 Nov; 13(1):1-4. PMID: 17123956
Kinetoplastid mitochondrial mRNA editing is a post-transcriptional process of uridine insertion and deletion. Editing is mediated by small RNA molecules termed guide RNAs (gRNAs). Most gRNAs are encoded by numerous...