Michael Chimenti
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Explore the profile of Michael Chimenti including associated specialties, affiliations and a list of published articles.
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6
Citations
838
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Recent Articles
1.
Petrin A, Machado-Paula L, Hinkle A, Hovey L, Awotoye W, Chimenti M, et al.
Cleft Palate Craniofac J
. 2025 Jan;
:10556656241306202.
PMID: 39819101
Objective: Oculoauriculovertebral spectrum (OAVS) encompasses abnormalities on derivatives from the first and second pharyngeal arches including macrostomia, hemifacial microsomia, micrognathia, preauricular tags, ocular, and vertebral anomalies. We present genetic findings...
2.
Guan X, Fury H, Issuree P, Atagozli T, McManimon E, Shao P, et al.
Int J Mol Sci
. 2025 Jan;
26(1.
PMID: 39796136
Bone marrow transplantation (BMT) is mainly performed to restore an anti-tumor immune response, called the graft-versus-tumor (GVT) effect, against leukemia, myeloma and lymphoma. This GVT reactivity is driven by donor...
3.
Awotoye W, Machado-Paula L, Hovey L, Keen H, Chimenti M, Darbro B, et al.
medRxiv
. 2024 Nov;
PMID: 39606391
Background: Disturbances in the intricate processes that control craniofacial morphogenesis can result in birth defects, most common of which are orofacial clefts (OFCs). Nonsyndromic cleft lip (nsCL), one of the...
4.
Cho Y, Vorn R, Chimenti M, Crouch K, Shaoshuai C, Narayanaswamy J, et al.
Front Nutr
. 2022 Oct;
9:976886.
PMID: 36313069
Background: Breast milk has abundant extracellular vesicles (EVs) containing various biological molecules (cargo), including miRNAs. EVs are not degraded in the gastrointestinal system and circulation; thus, breast milk EVs (bEVs)...
5.
Kumuthini J, Chimenti M, Nahnsen S, Peltzer A, Meraba R, McFadyen R, et al.
PLoS Comput Biol
. 2020 Mar;
16(3):e1007531.
PMID: 32214318
Life scientists are increasingly turning to high-throughput sequencing technologies in their research programs, owing to the enormous potential of these methods. In a parallel manner, the number of core facilities...
6.
Webb B, Chimenti M, Jacobson M, Barber D
Nat Rev Cancer
. 2011 Aug;
11(9):671-7.
PMID: 21833026
Although cancer is a diverse set of diseases, cancer cells share a number of adaptive hallmarks. Dysregulated pH is emerging as a hallmark of cancer because cancers show a 'reversed'...
7.
Schroer M, Paulus M, Jeworrek C, Krywka C, Schmacke S, Zhai Y, et al.
Biophys J
. 2010 Nov;
99(10):3430-7.
PMID: 21081092
A structural interpretation of the thermodynamic stability of proteins requires an understanding of the structural properties of the unfolded state. High-pressure small-angle x-ray scattering was used to measure the effects...
8.
Direct evidence for deprotonation of a lysine side chain buried in the hydrophobic core of a protein
Takayama Y, Castaneda C, Chimenti M, Garcia-Moreno B, Iwahara J
J Am Chem Soc
. 2008 May;
130(21):6714-5.
PMID: 18454523
We report direct evidence for deprotonation of a lysine side chain buried in the hydrophobic core of a protein, demonstrating heteronuclear 1H-15N NMR data on the Lys-66 side chain amine...