Michael Certo
Overview
Explore the profile of Michael Certo including associated specialties, affiliations and a list of published articles.
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6
Citations
990
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Recent Articles
1.
Castillo-Hair S, Fedak S, Wang B, Linder J, Havens K, Certo M, et al.
Nat Commun
. 2024 Jun;
15(1):5284.
PMID: 38902240
mRNA therapeutics are revolutionizing the pharmaceutical industry, but methods to optimize the primary sequence for increased expression are still lacking. Here, we design 5'UTRs for efficient mRNA translation using deep...
2.
Certo M, Arnold R
Ann Intern Med
. 2023 Jan;
176(1):JC7.
PMID: 36592463
Hui D, Puac V, Shelal Z, et al. Lancet Oncol. 2022;23:1321-31. 36087590.
3.
Stirling F, Naydich A, Bramante J, Barocio R, Certo M, Wellington H, et al.
Cell Rep
. 2020 Mar;
30(9):3139-3148.e4.
PMID: 32130913
As pH is fundamental to all biological processes, pH-responsive bacterial genetic circuits enable precise sensing in any environment. Where the unintentional release of engineered bacteria poses a concern, coupling pH...
4.
Takeuchi R, Certo M, Caprara M, Scharenberg A, Stoddard B
Nucleic Acids Res
. 2008 Dec;
37(3):877-90.
PMID: 19103658
The LAGLIDADG homing endonuclease (LHE) I-AniI has adopted an extremely efficient secondary RNA splicing activity that is beneficial to its host, balanced against inefficient DNA cleavage. A selection experiment identified...
5.
Gaizo Moore V, Brown J, Certo M, Love T, Novina C, Letai A
J Clin Invest
. 2007 Jan;
117(1):112-21.
PMID: 17200714
Antiapoptotic B cell leukemia/lymphoma 2 (BCL2) family proteins are expressed in many cancers, but the circumstances under which these proteins are necessary for tumor maintenance are poorly understood. We exploited...
6.
Certo M, Gaizo Moore V, Nishino M, Wei G, Korsmeyer S, Armstrong S, et al.
Cancer Cell
. 2006 May;
9(5):351-65.
PMID: 16697956
We show that the antiapoptotic proteins BCL-2, BCL-XL, MCL-1, BFL-1, and BCL-w each bear a unique pattern of interaction with a panel of peptides derived from BH3 domains of BH3-only...