Michael C Sheppard
Overview
Explore the profile of Michael C Sheppard including associated specialties, affiliations and a list of published articles.
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Articles
20
Citations
416
Followers
0
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Recent Articles
1.
Sherlock M, Reulen R, Aragon-Alonso A, Ayuk J, Clayton R, Sheppard M, et al.
J Clin Endocrinol Metab
. 2013 Nov;
99(2):478-85.
PMID: 24243636
Context: Acromegaly is associated with reduced life expectancy, which has been reported to be normalized if treatment is successful in controlling GH/IGF-I levels. Objective: Most previous studies have invariably used...
2.
Sherlock M, Woods C, Sheppard M
Nat Rev Endocrinol
. 2011 Mar;
7(5):291-300.
PMID: 21448141
Acromegaly is a rare disease characterized by excess secretion of growth hormone (GH) and increased circulating insulin-like growth factor 1 (IGF-1) concentrations. The disease is associated with increased morbidity and...
3.
Sherlock M, Ayuk J, Tomlinson J, Toogood A, Aragon-Alonso A, Sheppard M, et al.
Endocr Rev
. 2010 Jan;
31(3):301-42.
PMID: 20086217
Pituitary disease is associated with increased mortality predominantly due to vascular disease. Control of cortisol secretion and GH hypersecretion (and cardiovascular risk factor reduction) is key in the reduction of...
4.
Ayuk J, Sheppard M
Rev Endocr Metab Disord
. 2007 Dec;
9(1):33-9.
PMID: 18075787
The increased mortality associated with acromegaly was first demonstrated in early epidemiological studies. Since the seminal paper by Wright et al. in 1970, nearly 20 studies have analyzed mortality rates...
5.
6.
Osman F, Franklyn J, Holder R, Sheppard M, Gammage M
J Am Coll Cardiol
. 2007 Jan;
49(1):71-81.
PMID: 17207725
Objectives: This study sought to prospectively evaluate the prevalence of cardiovascular abnormalities in patients with overt hyperthyroidism before and after antithyroid therapy. Background: Overt hyperthyroidism is associated with recognized cardiovascular...
7.
Sheppard M
Nat Clin Pract Endocrinol Metab
. 2006 Oct;
2(10):532-3.
PMID: 17024147
No abstract available.
8.
Wilson S, Parle J, Roberts L, Roalfe A, Hobbs F, Clark P, et al.
J Clin Endocrinol Metab
. 2006 Sep;
91(12):4809-16.
PMID: 17003083
Context: Population-based screening has been advocated for subclinical thyroid dysfunction in the elderly because the disorder is perceived to be common, and health benefits may be accrued by detection and...
9.
Ayuk J, Sheppard M, Bates A, Stewart P
J Clin Endocrinol Metab
. 2005 Aug;
90(8):4980.
PMID: 16087964
No abstract available.
10.
Franklyn J, Sheppard M, Maisonneuve P
JAMA
. 2005 Jul;
294(1):71-80.
PMID: 15998893
Context: Hyperthyroidism has been reported to cause excess all-cause and circulatory mortality. Whether this can be reversed is unknown, as is the influence of mild persisting thyroid dysfunction and treatment-induced...