Michael C Mahaney
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Explore the profile of Michael C Mahaney including associated specialties, affiliations and a list of published articles.
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Articles
115
Citations
2519
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Recent Articles
1.
Li X, Chen H, Selvaraj M, Van Buren E, Zhou H, Wang Y, et al.
Nat Comput Sci
. 2025 Feb;
5(2):125-143.
PMID: 39920506
Large-scale whole-genome sequencing (WGS) studies have improved our understanding of the contributions of coding and noncoding rare variants to complex human traits. Leveraging association effect sizes across multiple traits in...
2.
de Vries P, Conomos M, Singh K, Nicholson C, Jain D, Hasbani N, et al.
Nat Cardiovasc Res
. 2024 May;
2(12):1159-1172.
PMID: 38817323
Coronary artery calcification (CAC) is a measure of atherosclerosis and a well-established predictor of coronary artery disease (CAD) events. Here we describe a genome-wide association study (GWAS) of CAC in...
3.
Diego V, Manusov E, Mao X, Almeida M, Peralta J, Curran J, et al.
Front Genet
. 2024 Mar;
15:1240462.
PMID: 38495670
Socioeconomic Status (SES) is a potent environmental determinant of health. To our knowledge, no assessment of genotype-environment interaction has been conducted to consider the joint effects of socioeconomic status and...
4.
Hasbani N, Westerman K, Kwak S, Chen H, Li X, Di Corpo D, et al.
Circ Genom Precis Med
. 2023 Nov;
16(6):e004176.
PMID: 38014529
Background: Individuals with type 2 diabetes (T2D) have an increased risk of coronary artery disease (CAD), but questions remain about the underlying pathology. Identifying which CAD loci are modified by...
5.
Li X, Chen H, Selvaraj M, Van Buren E, Zhou H, Wang Y, et al.
bioRxiv
. 2023 Nov;
PMID: 37961350
Large-scale whole-genome sequencing (WGS) studies have improved our understanding of the contributions of coding and noncoding rare variants to complex human traits. Leveraging association effect sizes across multiple traits in...
6.
Wang Y, Selvaraj M, Li X, Li Z, Holdcraft J, Arnett D, et al.
Am J Hum Genet
. 2023 Oct;
110(10):1704-1717.
PMID: 37802043
Long non-coding RNAs (lncRNAs) are known to perform important regulatory functions in lipid metabolism. Large-scale whole-genome sequencing (WGS) studies and new statistical methods for variant set tests now provide an...
7.
Diego V, Manusov E, Mao X, Curran J, Goring H, Almeida M, et al.
Front Genet
. 2023 Oct;
14:1132110.
PMID: 37795246
Socioeconomic status (SES) is a potent environmental determinant of health. To our knowledge, no assessment of genotype-environment interaction has been conducted to consider the joint effects of socioeconomic status and...
8.
Georgakis M, Malik R, El Bounkari O, Hasbani N, Li J, Huffman J, et al.
medRxiv
. 2023 Aug;
PMID: 37645892
Background: Previous work has shown a role of CCL2, a key chemokine governing monocyte trafficking, in atherosclerosis. However, it remains unknown whether targeting CCR2, the cognate receptor of CCL2, provides...
9.
Fongang B, Satizabal C, Kautz T, Wadop Y, Muhammad J, Vasquez E, et al.
Sci Rep
. 2023 Aug;
13(1):13622.
PMID: 37604954
A bidirectional communication exists between the brain and the gut, in which the gut microbiota influences cognitive function and vice-versa. Gut dysbiosis has been linked to several diseases, including Alzheimer's...
10.
Wang Y, Selvaraj M, Li X, Li Z, Holdcraft J, Arnett D, et al.
medRxiv
. 2023 Jul;
PMID: 37425772
Long non-coding RNAs (lncRNAs) are known to perform important regulatory functions. Large-scale whole genome sequencing (WGS) studies and new statistical methods for variant set tests now provide an opportunity to...