Michael Bur
Overview
Explore the profile of Michael Bur including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
153
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Recent Articles
1.
Lehmann A, Daum N, Bur M, Lehr C, Gehr P, Rothen-Rutishauser B
Eur J Pharm Biopharm
. 2010 Nov;
77(3):398-406.
PMID: 21056660
A triple cell co-culture model was recently established by the authors, consisting of either A549 or 16HBE14o- epithelial cells, human blood monocyte-derived macrophages and dendritic cells, which offers the possibility...
2.
Hein S, Bur M, Schaefer U, Lehr C
Eur J Pharm Biopharm
. 2010 Oct;
77(1):132-8.
PMID: 20951200
Absorption studies with aerosol formulation delivered by metered dose inhalers across cell- and tissue-based in vitro models of the pulmonary epithelia are not trivial due to the complexity of the...
3.
Hein S, Bur M, Kolb T, Muellinger B, Schaefer U, Lehr C
Altern Lab Anim
. 2010 Sep;
38(4):285-95.
PMID: 20822321
The development of aerosol medicines typically involves numerous tests on animals, due to the lack of adequate in vitro models. A new in vitro method for testing pharmaceutical aerosol formulations...
4.
Henning A, Hein S, Schneider M, Bur M, Lehr C
Handb Exp Pharmacol
. 2010 Mar;
(197):171-92.
PMID: 20217530
Mankind has inhaled substances for medical and other reasons for thousands of years, notably resulting in the cultural manifestations of tobacco and opium smoking. Over the course of time concepts...
5.
Gaschen A, Lang D, Kalberer M, Savi M, Geiser T, Gazdhar A, et al.
Environ Sci Technol
. 2010 Jan;
44(4):1424-30.
PMID: 20092303
The scope of this work was to examine in vitro responses of lung cells to secondary organic aerosol (SOA) particles, under realistic ambient air and physiological conditions occurring when particles...
6.
Bur M, Huwer H, Muys L, Lehr C
J Aerosol Med Pulm Drug Deliv
. 2010 Jan;
23(3):119-27.
PMID: 20073555
Background: Pulmonary cell cultures are increasingly used to predict in vivo drug absorption after inhalation, similar to intestinal cell culture models that have already been well established to predict oral...
7.
In vitro and in vivo performance of biocompatible negatively-charged salbutamol-loaded nanoparticles
Rytting E, Bur M, Cartier R, Bouyssou T, Wang X, Kruger M, et al.
J Control Release
. 2009 Sep;
141(1):101-7.
PMID: 19720096
The development and performance of a novel nanoparticle-based formulation for pulmonary delivery has been characterized chronologically through the particle preparation process, in vitro testing of drug release, biocompatibility, degradation, drug...
8.
Bur M, Henning A, Hein S, Schneider M, Lehr C
Inhal Toxicol
. 2009 Jun;
21 Suppl 1:137-43.
PMID: 19558246
Inhalation therapy is still limited by the low bioavailability of the administered drugs. Advantages of the pulmonary administration site like large resorption area, low enzymatic equipment, and circumvention of the...
9.
Daum N, Neumeyer A, Wahl B, Bur M, Lehr C
Methods Mol Biol
. 2008 Dec;
480:151-64.
PMID: 19085125
Biological barriers, typically, represented by epithelial tissues are the main hindrance against uncontrolled uptake of a variety of substances. However, the delivery across a biological barrier is a crucial factor...
10.
Bur M, Rothen-Rutishauser B, Huwer H, Lehr C
Eur J Pharm Biopharm
. 2008 Sep;
72(2):350-7.
PMID: 18771729
A modified Astra type multistage liquid impinger (MSLI) with integrated bronchial cell monolayers was used to study deposition and subsequent drug absorption on in vitro models of the human airway...