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Michael Brand

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Articles 194
Citations 5954
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Recent Articles
1.
Gupta M, Kurth T, Heinemann F, Schwille P, Keil S, Knopf F, et al.
Biophys J . 2024 Dec; PMID: 39668564
Embryonic development is orchestrated by the action of morphogens, which spread out from a local source and activate, in a field of target cells, different cellular programs based on their...
2.
Hammer J, Roppenack P, Yousuf S, Machate A, Fischer M, Hans S, et al.
Invest Ophthalmol Vis Sci . 2024 Nov; 65(13):42. PMID: 39565303
Purpose: Vision is the predominant sense in most animal species. Loss of vision can be caused by a multitude of factors resulting in anatomic as well as behavioral changes. In...
3.
Abraham E, Hartmann H, Yoshimatsu T, Baden T, Brand M
Dev Cell . 2024 Aug; 59(16):2158-2170.e6. PMID: 39096897
Unlike humans, teleosts like zebrafish exhibit robust retinal regeneration after injury from endogenous stem cells. However, it is unclear if regenerating cone photoreceptors regain physiological function and integrate correctly into...
4.
Bludau O, Weber A, Bosak V, Kuscha V, Dietrich K, Hans S, et al.
Front Cell Dev Biol . 2024 Jul; 12:1332347. PMID: 39071801
Inflammation can lead to persistent and irreversible loss of retinal neurons and photoreceptors in mammalian vertebrates. In contrast, in the adult zebrafish brain, acute neural inflammation is both necessary and...
5.
Horst F, Bodenstein E, Brand M, Hans S, Karsch L, Lessmann E, et al.
Radiother Oncol . 2024 Mar; 194:110197. PMID: 38447870
Purpose: A better characterization of the dependence of the tissue sparing effect at ultra-high dose rate (UHDR) on physical beam parameters (dose, dose rate, radiation quality) would be helpful towards...
6.
Metzkes-Ng J, Brack F, Kroll F, Bernert C, Bock S, Bodenstein E, et al.
Sci Rep . 2023 Nov; 13(1):20611. PMID: 37996453
The recently observed FLASH effect describes the observation of normal tissue protection by ultra-high dose rates (UHDR), or dose delivery in a fraction of a second, at similar tumor-killing efficacy...
7.
Celotto L, Rost F, Machate A, Blasche J, Dahl A, Weber A, et al.
Elife . 2023 Nov; 12. PMID: 37988404
In the lesioned zebrafish retina, Müller glia produce multipotent retinal progenitors that generate all retinal neurons, replacing lost cell types. To study the molecular mechanisms linking Müller glia reactivity to...
8.
Harish R, Brand M
Development . 2023 Oct; 150(19). PMID: 37787121
The growth factor Fgf8a has been suggested to act as a morphogen during zebrafish gastrulation, spreading from a localized source to form a concentration gradient and impart positional information to...
9.
Harish R, Gupta M, Zoller D, Hartmann H, Gheisari A, Machate A, et al.
Development . 2023 Sep; 150(19). PMID: 37665167
Morphogen gradients impart positional information to cells in a homogenous tissue field. Fgf8a, a highly conserved growth factor, has been proposed to act as a morphogen during zebrafish gastrulation. However,...
10.
Desch S, Freund A, Akin I, Behnes M, Preusch M, Zelniker T, et al.
JAMA Cardiol . 2023 Aug; 8(9):827-834. PMID: 37556123
Importance: Myocardial infarction is a frequent cause of out-of-hospital cardiac arrest (OHCA). The long-term effect of early coronary angiography on patients with OHCA with possible coronary trigger but no ST-segment...