Michael Borges
Overview
Explore the profile of Michael Borges including associated specialties, affiliations and a list of published articles.
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34
Citations
2287
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Recent Articles
1.
Kawamoto M, Kohi S, Abe T, Dbouk M, MacGregor-Das A, Koi C, et al.
Int J Cancer
. 2021 Nov;
150(7):1123-1133.
PMID: 34817877
Gene variants that encode pancreatic enzymes with impaired secretion can induce pancreatic acinar endoplasmic reticulum (ER) stress, cellular injury and pancreatitis. The role of such variants in pancreatic cancer risk...
2.
Tanaka H, Tamura K, Abe T, Yoshida T, MacGregor-Das A, Dbouk M, et al.
Clin Gastroenterol Hepatol
. 2021 Oct;
20(10):2267-2275.e2.
PMID: 34648951
Background And Aims: Serum diagnostic markers of early-stage pancreatic ductal adenocarcinoma (PDAC) are needed, especially for stage I disease. As tumors grow and cause pancreatic atrophy, markers derived from pancreatic...
3.
Zhou C, Porter N, Borges M, Gauthier C, Ferguson L, Huang B, et al.
Pancreatology
. 2021 Apr;
21(5):938-941.
PMID: 33839031
Background: Pancreatic cancer is a lethal disease with a poor 5-year survival rate. Pathogenic germline variants in the coding regions of ATM, BRCA1, and BRCA2 are found in up to...
4.
Kohi S, MacGregor-Das A, Dbouk M, Yoshida T, Chuidian M, Abe T, et al.
Clin Gastroenterol Hepatol
. 2020 Nov;
20(2):e196-e227.
PMID: 33161160
Background & Aims: The tumor microbiome of patients with pancreas ductal adenocarcinoma (PDAC) includes bacteria normally present in the upper gastrointestinal tract. If the predominant source of intratumoral bacteria in...
5.
MacGregor-Das A, Yu J, Tamura K, Abe T, Suenaga M, Shindo K, et al.
J Mol Diagn
. 2020 Mar;
22(6):748-756.
PMID: 32205290
Circulating tumor DNA (ctDNA) measurements can be used to estimate tumor burden, but avoiding false-positive results is challenging. Herein, digital next-generation sequencing (NGS) is evaluated as a ctDNA detection method....
6.
Abe T, Koi C, Kohi S, Song K, Tamura K, MacGregor-Das A, et al.
Clin Gastroenterol Hepatol
. 2019 Nov;
18(5):1161-1169.e5.
PMID: 31676359
Background & Aims: Levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), and cancer antigen 125 (CA-125) in blood are used as markers to determine the response of patients with...
7.
He H, Stein E, Konigshofer Y, Forbes T, Tomson F, Garlick R, et al.
J Mol Diagn
. 2019 May;
21(4):658-676.
PMID: 31055023
We conducted a multilaboratory assessment to determine the suitability of a new commercially available reference material with 40 cancer variants in a background of wild-type DNA at four different variant...
8.
Chen F, Childs E, Mocci E, Bracci P, Gallinger S, Li D, et al.
Cancer Epidemiol Biomarkers Prev
. 2019 Apr;
28(7):1238-1245.
PMID: 31015203
Background: Pancreatic cancer is the fourth-leading cause of cancer death in both men and women in the United States. The currently identified common susceptibility loci account for a small fraction...
9.
Abe T, Blackford A, Tamura K, Ford M, McCormick P, Chuidian M, et al.
J Clin Oncol
. 2019 Mar;
37(13):1070-1080.
PMID: 30883245
Purpose: To compare the risk of neoplastic progression by germline mutation status versus family history without a known germline mutation (familial risk) among individuals with an increased risk for pancreatic...
10.
Tamura K, Yu J, Hata T, Suenaga M, Shindo K, Abe T, et al.
Proc Natl Acad Sci U S A
. 2018 Apr;
115(18):4767-4772.
PMID: 29669919
To evaluate whether germline variants in genes encoding pancreatic secretory enzymes contribute to pancreatic cancer susceptibility, we sequenced the coding regions of and other genes encoding pancreatic secretory enzymes and...