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Michael Arand

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Articles 46
Citations 881
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Recent Articles
1.
Kastrinou-Lampou V, Rodriguez-Perez R, Poller B, Huth F, Schadt H, Kullak-Ublick G, et al.
Arch Toxicol . 2024 Nov; 99(1):377-391. PMID: 39542928
Drug-induced cholestasis (DIC) is recognized as a major safety concern in drug development, as it represents one of the three types of drug-induced liver injury (DILI). Cholestasis is characterized by...
2.
Fritsche E, Aspiroz L, Arand M, Faustman E, Muller I
ALTEX . 2024 Oct; 41(4):671-673. PMID: 39460461
No abstract available.
3.
Kastrinou-Lampou V, Rodriguez-Perez R, Poller B, Huth F, Gaborik Z, Martonne-Toth B, et al.
Arch Toxicol . 2024 Jul; 98(10):3409-3424. PMID: 39023798
Hepatic bile acid regulation is a multifaceted process modulated by several hepatic transporters and enzymes. Drug-induced cholestasis (DIC), a main type of drug-induced liver injury (DILI), denotes any drug-mediated condition...
4.
Dean-Ben X, Robin J, Nozdriukhin D, Ni R, Zhao J, Gluck C, et al.
Nat Commun . 2023 Jun; 14(1):3584. PMID: 37328490
Super-resolution optoacoustic imaging of microvascular structures deep in mammalian tissues has so far been impeded by strong absorption from densely-packed red blood cells. Here we devised 5 µm biocompatible dichloromethane-based...
5.
Kastrinou Lampou V, Poller B, Huth F, Fischer A, Kullak-Ublick G, Arand M, et al.
Toxicol In Vitro . 2022 Dec; 87:105533. PMID: 36473578
Bile acid (BA) homeostasis is a complex and precisely regulated process to prevent impaired BA flow and the development of cholestasis. Several reactions, namely hydroxylation, glucuronidation and sulfation are involved...
6.
Estrada H, Robin J, Ozbek A, Chen Z, Marowsky A, Zhou Q, et al.
Sci Adv . 2021 Dec; 7(50):eabi5464. PMID: 34878843
Understanding the physiological impact of transcranial ultrasound in rodent brains may offer an important preclinical model for human scale magnetic resonance–guided focused ultrasound methods. However, precision tools for high-resolution transcranial...
7.
Arand M
Arch Toxicol . 2021 Aug; 95(9):3137-3139. PMID: 34357440
No abstract available.
8.
Hartwig A, Arand M, Epe B, Guth S, Jahnke G, Lampen A, et al.
Arch Toxicol . 2020 Jul; 94(9):3347. PMID: 32696078
The author would like to thank N. Bakhiya, S. Hessel-Pras, B. Sachse, and B. Dusemund for their support in the chapter about pyrrolizidine alkaloids.
9.
Hartwig A, Arand M, Epe B, Guth S, Jahnke G, Lampen A, et al.
Arch Toxicol . 2020 Jun; 94(6):1787-1877. PMID: 32542409
The risk assessment of chemical carcinogens is one major task in toxicology. Even though exposure has been mitigated effectively during the last decades, low levels of carcinogenic substances in food...
10.
Erismann-Ebner K, Marowsky A, Arand M
Biosensors (Basel) . 2019 Mar; 9(1). PMID: 30823443
In previous studies, we encountered substantial problems using the CFP_YFP Förster resonance energy transfer (FRET) pair to analyze protein proximity in the endoplasmic reticulum of live cells. Bleed-through of the...