Michael Altenbuchinger
Overview
Explore the profile of Michael Altenbuchinger including associated specialties, affiliations and a list of published articles.
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37
Citations
236
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Recent Articles
1.
Seifert N, Reinke S, Grund J, Muller-Meinhard B, Richter J, Heilmann T, et al.
Leukemia
. 2024 Dec;
39(3):684-693.
PMID: 39690183
The Tumor Microenvironment (TME) in classical Hodgkin Lymphoma (HL) contains abundant immune cells and only few neoplastic Hodgkin and Reed-Sternberg cells (HRSC). We analyzed the T-cell receptor (TCR) repertoire to...
2.
Simeth J, Huttl P, Schon M, Nozari Z, Huttner M, Schmidt T, et al.
Bioinformatics
. 2024 Nov;
40(12).
PMID: 39589902
Motivation: Bulk RNA expression data are widely accessible, whereas single-cell data are relatively scarce in comparison. However, single-cell data offer profound insights into the cellular composition of tissues and cell...
3.
Schrod S, Luck N, Lohmayer R, Solbrig S, Volkl D, Wipfler T, et al.
Genome Res
. 2024 Sep;
34(9):1371-1383.
PMID: 39231609
Advances in omics technologies have allowed spatially resolved molecular profiling of single cells, providing a window not only into the diversity and distribution of cell types within a tissue, but...
4.
Gortler F, Mensching-Buhr M, Skaar O, Schrod S, Sterr T, Schafer A, et al.
Bioinformatics
. 2024 Jun;
40(Suppl 1):i100-i109.
PMID: 38940181
Motivation: The inference of cellular compositions from bulk and spatial transcriptomics data increasingly complements data analyses. Multiple computational approaches were suggested and recently, machine learning techniques were developed to systematically...
5.
Schrod S, Zacharias H, Beissbarth T, Hauschild A, Altenbuchinger M
Bioinformatics
. 2024 Jun;
40(Suppl 1):i91-i99.
PMID: 38940173
Motivation: High-throughput screens (HTS) provide a powerful tool to decipher the causal effects of chemical and genetic perturbations on cancer cell lines. Their ability to evaluate a wide spectrum of...
6.
Muller-Meinhard B, Seifert N, Grund J, Reinke S, Yalcin F, Kaul H, et al.
Hemasphere
. 2024 Jun;
8(6):e84.
PMID: 38836098
Hodgkin-Reed-Sternberg cells (HRSCs) in classic Hodgkin Lymphoma (HL) frequently lack expression of human leukocyte antigen class I (HLA-I), considered to hamper activation of cytotoxic T cells in the tumor microenvironment...
7.
Steinbrenner I, Kotsis F, Kosch R, Meiselbach H, Barthlein B, Stockmann H, et al.
Nephrol Dial Transplant
. 2024 Apr;
39(12):2016-2024.
PMID: 38664006
Background: Persons with chronic kidney disease (CKD) are at increased risk of adverse events, early mortality and multimorbidity. A detailed overview of adverse event types and rates from a large...
8.
Kotsis F, Bachle H, Altenbuchinger M, Donitz J, Njipouombe Nsangou Y, Meiselbach H, et al.
BMC Med Inform Decis Mak
. 2023 Oct;
23(1):239.
PMID: 37884906
Background: Chronic kidney disease (CKD), a major public health problem with differing disease etiologies, leads to complications, comorbidities, polypharmacy, and mortality. Monitoring disease progression and personalized treatment efforts are crucial...
9.
Buck L, Schmidt T, Feist M, Schwarzfischer P, Kube D, Oefner P, et al.
Bioinformatics
. 2023 Aug;
39(8).
PMID: 37584673
Motivation: Mixed molecular data combines continuous and categorical features of the same samples, such as OMICS profiles with genotypes, diagnoses, or patient sex. Like all high-dimensional molecular data, it is...
10.
Treiber H, Nilius-Eliliwi V, Seifert N, Vangala D, Wang M, Seidel S, et al.
Hemasphere
. 2023 Jul;
7(8):e926.
PMID: 37492436
Secondary central nervous system lymphoma (SCNSL) is a rare and difficult to treat type of Non-Hodgkin lymphoma characterized by systemic and central nervous system (CNS) disease manifestations. In this study,...