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Michael A Zasloff

Explore the profile of Michael A Zasloff including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 467
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Recent Articles
1.
Cardoso M, de la Fuente-Nunez C, Santos N, Zasloff M, Franco O
Trends Microbiol . 2024 May; 32(7):624-627. PMID: 38777700
Many factors contribute to bacterial membrane stabilization, including steric effects between lipids, membrane spontaneous curvature, and the difference in the number of neighboring molecules. This forum provides an overview of...
2.
Zhang L, Qin Z, Sharmin F, Lin W, Ricke K, Zasloff M, et al.
Neurobiol Dis . 2021 May; 156:105402. PMID: 34044147
Mutations in the beta-amyloid protein (APP) cause familial Alzheimer's disease. In hAPP-J20 mice expressing mutant APP, pharmacological inhibition or genetic ablation of the tyrosine phosphatase PTP1B prevents CA3 hippocampus neuron...
3.
Qin Z, Zhang L, Zasloff M, Stewart A, Chen H
Neurobiol Dis . 2021 May; 155:105397. PMID: 34015491
Subanesthetic doses of ketamine induce schizophrenia-like behaviors in mice including hyperlocomotion and deficits in working memory and sensorimotor gating. Here, we examined the effect of in vivo ketamine administration on...
4.
Ricke K, Cruz S, Qin Z, Farrokhi K, Sharmin F, Zhang L, et al.
J Neurosci . 2020 Jan; 40(7):1581-1593. PMID: 31915254
Alzheimer's disease (AD) is the most common neurodegenerative disorder, resulting in the progressive decline of cognitive function in patients. Familial forms of AD are tied to mutations in the amyloid...
5.
Civitello M, Denton R, Zasloff M, Malone J
G3 (Bethesda) . 2019 Jan; 9(2):581-589. PMID: 30606754
The skin secretions of many frogs have genetically-encoded, endogenous antimicrobial peptides (AMPs). Other species, especially aposematic poison frogs, secrete exogenously derived alkaloids that serve as potent defense molecules. The origins...
6.
Smith A, Maguire-Nguyen K, Rando T, Zasloff M, Strange K, Yin V
NPJ Regen Med . 2018 Jan; 2:4. PMID: 29302341
Regenerative medicine holds substantial promise for repairing or replacing tissues and organs damaged by disease, injury, and degeneration. Much of the field has focused on development of cell-based therapeutics, gene-based...
7.
Stolzenberg E, Berry D, Yang D, Lee E, Kroemer A, Kaufman S, et al.
J Innate Immun . 2017 Jun; 9(5):456-463. PMID: 28651250
Background: Alpha-synuclein (αS) is a nerve cell protein associated with Parkinson disease (PD). Accumulation of αS within the enteric nervous system (ENS) and its traffic from the gut to the...
8.
Matsumoto C, Zasloff M, Fishbein T
Curr Opin Organ Transplant . 2014 Apr; 19(3):276-80. PMID: 24752065
Purpose Of Review: The purpose of this review is to highlight the similarities between inflammatory bowel disease and the state of the intestine allograft after transplantation. Recent Findings: The mutant...
9.
Kaplan F, Zasloff M, Kitterman J, Shore E, Hong C, Rocke D
J Bone Joint Surg Am . 2010 Mar; 92(3):686-91. PMID: 20194327
Background: Fibrodysplasia ossificans progressiva, a rare genetic disorder of progressive extraskeletal ossification, is the most disabling form of heterotopic ossification in humans. However, little is known about the lifespan or...
10.
Chernova M, Vandorpe D, Clark J, Williams J, Zasloff M, Jiang L, et al.
Am J Physiol Regul Integr Comp Physiol . 2005 Aug; 289(6):R1644-58. PMID: 16109810
The shark liver antimicrobial polyaminosterol squalamine is an angiogenesis inhibitor under clinical investigation as an anti-cancer agent and as a treatment for the choroidal neovascularization associated with macular degeneration of...