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Alexandre F R Stewart

Explore the profile of Alexandre F R Stewart including associated specialties, affiliations and a list of published articles. Areas
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Articles 118
Citations 7228
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Barbut D, Kinney W, Chen H, Stewart A, Hecksher-Sorensen J, Zhang C, et al.
Diabetes Obes Metab . 2024 Sep; 26(12):5701-5712. PMID: 39307948
ENT-03, a spermine bile acid we recently discovered in the brain of newborn mice acts centrally to regulate energy and metabolism. Obese, diabetic (ob/ob) mice treated with five doses of...
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Schormair B, Zhao C, Bell S, Didriksen M, Nawaz M, Schandra N, et al.
Nat Genet . 2024 Jun; 56(6):1090-1099. PMID: 38839884
Restless legs syndrome (RLS) affects up to 10% of older adults. Their healthcare is impeded by delayed diagnosis and insufficient treatment. To advance disease prediction and find new entry points...
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Zelt J, Cadete V, Deng Y, Godoy R, Cuillerier A, Rowe K, et al.
Hypertension . 2022 Oct; 79(12):2774-2786. PMID: 36278405
Background: We explored the mechanism of maladaptive right ventricular (RV) remodeling in Fischer compared with Sprague-Dawley (SD) rats exposed to pressure overload. Methods: Pulmonary hypertension was induced by injection of...
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Vilmundarson R, Heydarikhorneh N, Duong A, Ho T, Keyhanian K, Soheili F, et al.
Front Immunol . 2022 Jul; 13:868053. PMID: 35865523
Interferon regulatory factor 2 binding protein 2 (Irf2bp2), a co-repressor of Irf2, is required for fetal hepatic erythropoiesis through the expansion of erythromyeloid progenitors. Mice with germline ablation of the...
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Stewart A, Chen H
Viruses . 2022 Mar; 14(3). PMID: 35336966
Human breast cancer incidence varies by geographic location. More than 20 years ago, we proposed that zoonotic transmission of the mouse mammary tumor virus (MMTV) from the western European house...
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Vilmundarson R, Duong A, Soheili F, Chen H, Stewart A
Front Cardiovasc Med . 2021 Nov; 8:687645. PMID: 34760935
Interferon regulatory factor 2 binding protein 2 (IRF2BP2) suppresses the innate inflammatory response of macrophages. A 9-nucleotide deletion (rs3045215) in the 3' untranslated region (3'-UTR) of human IRF2BP2 mRNA confers...
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Audain E, Wilsdon A, Breckpot J, Izarzugaza J, Fitzgerald T, Kahlert A, et al.
PLoS Genet . 2021 Sep; 17(9):e1009809. PMID: 34547032
[This corrects the article DOI: 10.1371/journal.pgen.1009679.].
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Audain E, Wilsdon A, Breckpot J, Izarzugaza J, Fitzgerald T, Kahlert A, et al.
PLoS Genet . 2021 Jul; 17(7):e1009679. PMID: 34324492
Numerous genetic studies have established a role for rare genomic variants in Congenital Heart Disease (CHD) at the copy number variation (CNV) and de novo variant (DNV) level. To identify...