Michael A Schwarzschild
Overview
Explore the profile of Michael A Schwarzschild including associated specialties, affiliations and a list of published articles.
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210
Citations
7827
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Recent Articles
1.
Ngo H, Srivastava A, Le H, Ayer S, Crotty G, Schwarzschild M, et al.
BMC Neurosci
. 2025 Mar;
26(1):19.
PMID: 40038582
Background: The G2019S mutation of LRRK2, which enhances kinase activity of the protein, confers a substantial risk of developing Parkinson's disease (PD). However, the mutation demonstrates incomplete penetrance, suggesting the...
2.
Chen X, Li Y, Shen Y, Schwarzschild M, Gao X
NPJ Parkinsons Dis
. 2025 Jan;
11(1):14.
PMID: 39779712
Association of prodromal Parkinson's disease (PD) with risk of PD and risk of mortality in individuals with PD warrant investigation through large-scale prospective study. We included 501,475 participants without PD...
3.
Schootemeijer S, de Vries N, Darweesh S, Ascherio A, Schwarzschild M, Macklin E, et al.
J Neurol Phys Ther
. 2025 Jan;
PMID: 39763021
Background And Purpose: Physical activity has beneficial symptomatic effects for people with Parkinson's disease (PD), but increasing-and sustaining-a physically active lifestyle remains challenging. We investigated the feasibility (ability to increase...
4.
Flores-Torres M, Hughes K, Cortese M, Hung A, Healy B, Schwarzschild M, et al.
Ann Neurol
. 2024 Dec;
97(4):720-729.
PMID: 39702948
Objective: We prospectively evaluated how well combinations of signs and symptoms can identify individuals in the prodromal phase of Parkinson's disease (PD). Methods: The study comprised 6,108 men who underwent...
5.
Crotty G, Ayer S, Schwarzschild M
J Parkinsons Dis
. 2024 Sep;
14(s2):S381-S393.
PMID: 39302381
For decades the greatest goal of Parkinson's disease (PD) research has often been distilled to the discovery of treatments that prevent the disease or its progression. However, until recently only...
6.
Cook L, Verbrugge J, Schwantes-An T, Schulze J, Foroud T, Hall A, et al.
Brain
. 2024 Jul;
147(8):2668-2679.
PMID: 39074992
Variants in seven genes (LRRK2, GBA1, PRKN, SNCA, PINK1, PARK7 and VPS35) have been formally adjudicated as causal contributors to Parkinson's disease; however, individuals with Parkinson's disease are often unaware...
7.
Wyse R, Isaacs T, Barker R, Cookson M, Dawson T, Devos D, et al.
J Parkinsons Dis
. 2024 Apr;
14(4):657-666.
PMID: 38578902
In 2011, the UK medical research charity Cure Parkinson's set up the international Linked Clinical Trials (iLCT) committee to help expedite the clinical testing of potentially disease modifying therapies for...
8.
Ngo H, Le H, Ayer S, Crotty G, Schwarzschild M, Bakshi R
Res Sq
. 2024 Apr;
PMID: 38562908
Background: The G2019S mutation of LRRK2, which enhances kinase activity of the protein, confers a substantial risk of developing Parkinson's disease (PD). However, the mutation demonstrates incomplete penetrance, suggesting the...
9.
Keavney J, Mathur S, Schroeder K, Merrell R, Castillo-Torres S, Gao V, et al.
J Parkinsons Dis
. 2024 Mar;
14(3):399-414.
PMID: 38489198
The movement toward prevention trials in people at-risk for Parkinson's disease (PD) is rapidly becoming a reality. The authors of this article include a genetically at-risk advocate with the LRRK2...
10.
Rose K, Schwarzschild M, Gomperts S
Mov Disord
. 2024 Jan;
39(2):267-272.
PMID: 38226487
The link between smoking and a lower risk of Parkinson's disease (PD) is one of the strongest environmental or lifestyle associations in neuroepidemiology. Growing evidence supports the hypothesis that the...