Michael A Schmid
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Explore the profile of Michael A Schmid including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
2416
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Recent Articles
1.
Rosen L, Tortorici M, De Marco A, Pinto D, Foreman W, Taylor A, et al.
Cell
. 2024 Oct;
187(25):7196-7213.e26.
PMID: 39383863
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evolution has resulted in viral escape from clinically authorized monoclonal antibodies (mAbs), creating a need for mAbs that are resilient to epitope diversification....
2.
Plotnik D, Sager J, Aryal M, Fanget M, Peter A, Schmid M, et al.
Antimicrob Agents Chemother
. 2024 Feb;
68(4):e0127323.
PMID: 38376227
The objective of this study was to evaluate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of VIR-2482 in healthy adult subjects. A phase 1, first-in-human, randomized, double-blind, placebo-controlled dose-escalation study...
3.
Addetia A, Piccoli L, Case J, Park Y, Beltramello M, Guarino B, et al.
Nature
. 2023 Aug;
621(7979):592-601.
PMID: 37648855
Currently circulating SARS-CoV-2 variants have acquired convergent mutations at hot spots in the receptor-binding domain (RBD) of the spike protein. The effects of these mutations on viral infection and transmission...
4.
Lempp F, Volz T, Cameroni E, Benigni F, Zhou J, Rosen L, et al.
J Hepatol
. 2023 Jul;
79(5):1129-1138.
PMID: 37459920
Background & Aims: Chronic hepatitis B is a global public health problem, and coinfection with hepatitis delta virus (HDV) worsens disease outcome. Here, we describe a hepatitis B virus (HBV)...
5.
Momont C, Dang H, Zatta F, Hauser K, Wang C, di Iulio J, et al.
Nature
. 2023 Jul;
619(7970):E50.
PMID: 37407829
No abstract available.
6.
Momont C, Dang H, Zatta F, Hauser K, Wang C, di Iulio J, et al.
Nature
. 2023 May;
618(7965):590-597.
PMID: 37258672
Rapidly evolving influenza A viruses (IAVs) and influenza B viruses (IBVs) are major causes of recurrent lower respiratory tract infections. Current influenza vaccines elicit antibodies predominantly to the highly variable...
7.
Addetia A, Piccoli L, Case J, Park Y, Beltramello M, Guarino B, et al.
bioRxiv
. 2023 Jan;
PMID: 36711984
Currently circulating SARS-CoV-2 variants acquired convergent mutations at receptor-binding domain (RBD) hot spots. Their impact on viral infection, transmission, and efficacy of vaccines and therapeutics remains poorly understood. Here, we...
8.
Aweda T, Cheng S, Lenhard S, Sepp A, Skedzielewski T, Hsu C, et al.
Eur J Nucl Med Mol Imaging
. 2022 Oct;
50(3):667-678.
PMID: 36305907
Purpose: Sotrovimab (VIR-7831), a human IgG1κ monoclonal antibody (mAb), binds to a conserved epitope on the SARS-CoV-2 spike protein receptor binding domain (RBD). The Fc region of VIR-7831 contains an...
9.
Park Y, Pinto D, Walls A, Liu Z, De Marco A, Benigni F, et al.
Science
. 2022 Oct;
378(6620):619-627.
PMID: 36264829
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages carry distinct spike mutations resulting in escape from antibodies induced by previous infection or vaccination. We show that hybrid immunity or...
10.
Case J, Mackin S, Errico J, Chong Z, Madden E, Whitener B, et al.
Nat Commun
. 2022 Jul;
13(1):3824.
PMID: 35780162
Omicron variant strains encode large numbers of changes in the spike protein compared to historical SARS-CoV-2 isolates. Although in vitro studies have suggested that several monoclonal antibody therapies lose neutralizing...