Michael A McDannald
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Explore the profile of Michael A McDannald including associated specialties, affiliations and a list of published articles.
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49
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1241
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Recent Articles
1.
Williams D, Chu A, Gordon N, DuBois A, Qian S, Valvo G, et al.
Elife
. 2025 Mar;
14.
PMID: 40029045
Recognizing and responding to threat cues is essential to survival. Freezing is a predominant threat behavior in rats. We have recently shown that a threat cue can organize diverse behaviors...
2.
Russell E, McDannald M
eNeuro
. 2024 Nov;
11(11).
PMID: 39510838
Fear generalization is a hallmark of anxiety disorders. Experimentally, fear generalization can be difficult to dissociate from its counterpart, fear discrimination. Here, we use minimal threat learning procedures to reveal...
3.
Williams D, Chu A, Gordon N, DuBois A, Qian S, Valvo G, et al.
bioRxiv
. 2024 Sep;
PMID: 39314414
Recognizing and responding to threat cues is essential to survival. In rats, freezing is the most common behavior measured. Previously we demonstrated a threat cue can organize diverse behaviors (Chu...
4.
Chu A, Gordon N, DuBois A, Michel C, Hanrahan K, Williams D, et al.
Elife
. 2024 May;
13.
PMID: 38770736
Pavlovian fear conditioning has been extensively used to study the behavioral and neural basis of defensive systems. In a typical procedure, a cue is paired with foot shock, and subsequent...
5.
McDannald M
J Neurosci
. 2023 Nov;
43(48):8079-8087.
PMID: 38030400
A common neuroscience application of Pavlovian fear conditioning is to manipulate neuron-type activity, pair a cue with foot shock, then measure cue-elicited freezing in a novel context. If the manipulation...
6.
Wright K, Cieslewski S, Chu A, McDannald M
Behav Neurosci
. 2023 Oct;
137(6):347-355.
PMID: 37796586
Defensive responding is adaptive when it approximates the current threat but maladaptive when it exceeds the current threat. Here we asked if the substantia nigra, a region consistently implicated in...
7.
Wright K, Cieslewski S, Chu A, McDannald M
bioRxiv
. 2023 Feb;
PMID: 36824795
Defensive responding is adaptive when it approximates current threat, but maladaptive when it exceeds current threat. Here we asked if the substantia nigra, a region consistently implicated in reward, is...
8.
Wright K, Kantor C, Moaddab M, McDannald M
bioRxiv
. 2023 Feb;
PMID: 36747855
Behavioral responding is most beneficial when it reflects event timing. Compared to reward, there are fewer studies on timing of defensive responding. We gave female and male rats Pavlovian fear...
9.
Strickland J, McDannald M
Nat Commun
. 2022 Oct;
13(1):6192.
PMID: 36261515
When faced with potential threat we must estimate its probability, respond advantageously, and leverage experience to update future estimates. Threat estimation is the proposed domain of the forebrain, while behaviour...
10.
Walker R, Suthard R, Perison T, Sheehan N, Dwyer C, Lee J, et al.
eNeuro
. 2022 Jan;
9(1).
PMID: 35078807
The dorsal raphe nucleus (DRN) contains the largest population of serotonin (5-HT) neurons in the central nervous system. 5-HT, synthesized via tryptophan hydroxylase 2 (Tph2), is a widely functioning neuromodulator...