Michael A Bruckman
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Explore the profile of Michael A Bruckman including associated specialties, affiliations and a list of published articles.
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21
Citations
495
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Recent Articles
1.
Li L, Menendez-Lustri D, Hartzler A, Pogharian A, Zaorski B, Chen A, et al.
Biomaterials
. 2025 Jan;
317:123082.
PMID: 39787896
Intracortical microelectrodes (IMEs) are essential for neural signal acquisition in neuroscience and brain-machine interface (BMI) systems, aiding patients with neurological disorders, paralysis, and amputations. However, IMEs often fail to maintain...
2.
Srinivasan A, Secunda Z, Mota-Alvidrez R, Luc N, Disharoon D, Traylor B, et al.
J Trauma Acute Care Surg
. 2023 Dec;
96(1):101-108.
PMID: 38057963
Background: Early platelet transfusion is associated with reduced mortality in traumatic hemorrhage. However, platelet usage is severely limited because of the challenges of donor availability, platelet portability, and storage. Here,...
3.
Topical Synthetic Platelets Loaded With Gentamicin Decrease Bacteria in Deep Partial-Thickness Burns
Valdera F, Nuutila K, Varon D, Cooper L, Chapa J, Christy S, et al.
J Surg Res
. 2023 Jul;
291:167-175.
PMID: 37422958
Introduction: Prolonged inflammation and infection in burns may cause inadequate healing. Platelet granules contain anti-inflammatory mediators that impact wound healing. Synthetic platelets (SPs) avoid portability and storage difficulties of natural...
4.
Guillaumin J, Satchell P, Yaxley P, Bruckman M, Sen Gupta A
Am J Vet Res
. 2022 Jul;
83(10).
PMID: 35895758
Objective: To assess the safety and efficacy of the platelet-like nanoparticle (PLN), and to assess its safety in repeated administration. Animals: 6 purpose-bred dogs. Procedures: The PLN was administered IV...
5.
Bruckman M, Czapar A, Steinmetz N
Methods Mol Biol
. 2018 Jun;
1776:425-436.
PMID: 29869258
Nature has designed nanosized particles, specifically viruses, equipped to deliver cargo to cells. We report the chemical bioconjugation and shape shifting of a hollow, rod-shaped tobacco mosaic virus (TMV) to...
6.
Bruckman M, Czapar A, VanMeter A, Randolph L, Steinmetz N
J Control Release
. 2016 Mar;
231:103-13.
PMID: 26941034
Drug delivery systems are required for drug targeting to avoid adverse effects associated with chemotherapy treatment regimes. Our approach is focused on the study and development of plant virus-based materials...
7.
Worden M, Bruckman M, Kim M, Steinmetz N, Kikkawa J, LaSpina C, et al.
J Mater Chem B
. 2015 Dec;
3(34):6877-6884.
PMID: 26693011
A low temperature, aqueous synthesis of polyhedral iron oxide nanoparticles (IONPs) is presented. The modification of the co-precipitation hydrolysis method with Triton X surfactants results in the formation of crystalline...
8.
Silica-coated Gd(DOTA)-loaded protein nanoparticles enable magnetic resonance imaging of macrophages
Bruckman M, Randolph L, Gulati N, Stewart P, Steinmetz N
J Mater Chem B
. 2015 Dec;
3(38):7503-7510.
PMID: 26659591
The molecular imaging of targets allows non-invasive disease diagnosis. Nanoparticles offer a promising platform for molecular imaging because they can deliver large payloads of imaging reagents to the site of...
9.
Bruckman M, VanMeter A, Steinmetz N
ACS Biomater Sci Eng
. 2015 May;
1(1):13-18.
PMID: 25984569
Nanomanufacturing of nanoparticles is critical for potential translation and commercialization. Continuous flow devices can alleviate this need through unceasing production of nanoparticles. Here we demonstrate the scaled-up production of spherical...
10.
Bruckman M, Jiang K, Simpson E, Randolph L, Luyt L, Yu X, et al.
Nano Lett
. 2014 Feb;
14(3):1551-8.
PMID: 24499194
The underlying cause of major cardiovascular events, such as myocardial infarctions and strokes, is atherosclerosis. For accurate diagnosis of this inflammatory disease, molecular imaging is required. Toward this goal, we...