Merrill J Egorin
Overview
Explore the profile of Merrill J Egorin including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
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147
Citations
3349
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Recent Articles
1.
Fracasso P, Fisher Jr G, Goodner S, Beumer J, Egorin M, Fears C, et al.
Am J Clin Oncol
. 2023 Jun;
46(8):353-359.
PMID: 37264515
Objectives: Multidrug resistance mediated by P-glycoprotein is a potential obstacle to cancer treatment. This phase 1 trial determined the safety of paclitaxel with valspodar, a P-glycoprotein inhibitor, in patients with...
2.
Jaeckle K, Anderson S, Twohy E, Dixon J, Giannini C, Jenkins R, et al.
J Neurooncol
. 2019 Jun;
143(3):583.
PMID: 31165953
The last author's first name was truncated in the initial online publication. The original article has been corrected.
3.
Jaeckle K, Anderson S, Twohy E, Dixon J, Giannini C, Jenkins R, et al.
J Neurooncol
. 2019 May;
143(3):573-581.
PMID: 31119479
Purpose: To evaluate the pharmacokinetics and efficacy of imatinib in patients with recurrent oligodendroglial tumors. Methods: Patients with progressive WHO grade II-III recurrent tumors after prior RT and chemotherapy were...
4.
Lee D, Zhang Y, Kassam A, Park M, Gardner P, Prevedello D, et al.
PLoS One
. 2015 Aug;
10(8):e0134426.
PMID: 26247786
Background: The majority of chordomas show activation of the platelet-derived growth factor receptor (PDGFR). Based on in vitro intertumoral variation in response to recombinant PDGF protein and PDGFR inhibition, and...
5.
Parise R, Eiseman J, Clausen D, Kicielinski K, Hershberger P, Egorin M, et al.
Cancer Chemother Pharmacol
. 2015 Jul;
76(3):537-46.
PMID: 26193988
Introduction: Benzaldehyde dimethane sulfonate (BEN, DMS612, NSC281612) is a bifunctional alkylating agent currently in clinical trials. We previously characterized the degradation products of BEN in plasma and blood. The conversion...
6.
Muzzio M, Hu S, Holleran J, Parise R, Eiseman J, Yellow-Duke A, et al.
Cancer Chemother Pharmacol
. 2015 Mar;
75(5):1015-23.
PMID: 25776905
Purpose: NSC 743400 is a novel synthetic indenoisoquinoline analog under development as an anticancer agent. It is a potent topoisomerase I inhibitor with potential therapeutic advantages over FDA-approved camptothecin derivatives....
7.
How J, Minden M, Brian L, Chen E, Brandwein J, Schuh A, et al.
Leuk Lymphoma
. 2015 Feb;
56(10):2793-802.
PMID: 25682963
This phase I trial evaluated two schedules of escalating vorinostat in combination with decitabine every 28 days: (i) sequential or (ii) concurrent. There were three dose-limiting toxicities: grade 3 fatigue...
8.
Beumer J, Owzar K, Lewis L, Jiang C, Holleran J, Christner S, et al.
Cancer Chemother Pharmacol
. 2014 Aug;
74(5):927-38.
PMID: 25163570
Purpose: Older patients with acute myeloid leukemia (AML) and myelodysplastic syndrome have often been excluded from myeloablative-conditioning regimens containing busulfan because of non-disease-related morbidity and mortality. We hypothesized that busulfan...
9.
Tawbi H, Tran A, Christner S, Lin Y, Johnson M, Mowrey E, et al.
Cancer Chemother Pharmacol
. 2013 Sep;
72(5):1143-7.
PMID: 24036846
What Is Already Known About This Subject: Gastric upset is a common side effect of nilotinib therapy, and calcium carbonate is frequently used concomitantly, either as antacid or as calcium...
10.
Lewis L, Miller A, Owzar K, Bies R, Markova S, Jiang C, et al.
Pharmacogenet Genomics
. 2012 Nov;
23(1):29-33.
PMID: 23188068
Docetaxel-related neutropenia was associated with polymorphisms in the drug transporters ABCC2 and SLCO1B3 in Japanese cancer patients. We hypothesized that this association is because of reduced docetaxel clearance, associated with...