Meriem El Karoui
Overview
Explore the profile of Meriem El Karoui including associated specialties, affiliations and a list of published articles.
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23
Citations
1218
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Recent Articles
1.
Scorza L, Zielinski T, Kalita I, Lepore A, El Karoui M, Millar A
Wellcome Open Res
. 2024 Oct;
9:523.
PMID: 39360219
Background: Data reusability is the driving force of the research data life cycle. However, implementing strategies to generate reusable data from the data creation to the sharing stages is still...
2.
Lansch-Justen L, El Karoui M, Alexander H
PLoS Comput Biol
. 2024 May;
20(5):e1012146.
PMID: 38805543
Exposure to environmental stressors, including certain antibiotics, induces stress responses in bacteria. Some of these responses increase mutagenesis and thus potentially accelerate resistance evolution. Many studies report increased mutation rates...
3.
Yaseen I, White S, Torres-Garcia S, Spanos C, Lafos M, Gaberdiel E, et al.
Nat Struct Mol Biol
. 2022 Jul;
29(8):745-758.
PMID: 35879419
Epe1 histone demethylase restricts H3K9-methylation-dependent heterochromatin, preventing it from spreading over, and silencing, gene-containing regions in fission yeast. External stress induces an adaptive response allowing heterochromatin island formation that confers...
4.
Jaramillo-Riveri S, Broughton J, McVey A, Pilizota T, Scott M, El Karoui M
Mol Syst Biol
. 2022 May;
18(5):e10441.
PMID: 35620827
In natural environments, bacteria are frequently exposed to sub-lethal levels of DNA damage, which leads to the induction of a stress response (the SOS response in Escherichia coli). Natural environments...
5.
El Karoui M, Hoyos-Flight M, Fletcher L
Front Bioeng Biotechnol
. 2019 Aug;
7:175.
PMID: 31448268
Leading researchers working on synthetic biology and its applications gathered at the University of Edinburgh in May 2018 to discuss the latest challenges and opportunities in the field. In addition...
6.
Kapanidis A, Lepore A, El Karoui M
Biophys J
. 2018 Apr;
115(2):190-202.
PMID: 29680157
Bacteria are microorganisms central to health and disease, serving as important model systems for our understanding of molecular mechanisms and for developing new methodologies and vehicles for biotechnology. In the...
7.
Paulsson J, El Karoui M, Lindell M, Hughes D
Mol Microbiol
. 2017 Mar;
104(5):752-760.
PMID: 28256783
Gene conversion, non-reciprocal transfer from one homologous sequence to another, is a major force in evolutionary dynamics, promoting co-evolution in gene families and maintaining similarities between repeated genes. However, the...
8.
Okumus B, Landgraf D, Lai G, Bakshi S, Arias-Castro J, Yildiz S, et al.
Nat Commun
. 2016 Jun;
7:12130.
PMID: 27338979
No abstract available.
9.
Okumus B, Landgraf D, Lai G, Bakshi S, Arias-Castro J, Yildiz S, et al.
Nat Commun
. 2016 May;
7:11641.
PMID: 27189321
Many key regulatory proteins in bacteria are present in too low numbers to be detected with conventional methods, which poses a particular challenge for single-cell analyses because such proteins can...
10.
Cockram C, Filatenkova M, Danos V, El Karoui M, Leach D
Proc Natl Acad Sci U S A
. 2015 Aug;
112(34):E4735-42.
PMID: 26261330
Understanding molecular mechanisms in the context of living cells requires the development of new methods of in vivo biochemical analysis to complement established in vitro biochemistry. A critically important molecular...