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Mereena George Ushakumary

Explore the profile of Mereena George Ushakumary including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 65
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Recent Articles
1.
Titus A, Ushakumary M, Venugopal H, Wang M, Lakatta E, Kailasam S
Int J Mol Sci . 2023 Jan; 24(1). PMID: 36614028
Molecular mechanisms underlying the diverse therapeutic effects of anti-diabetic metformin, beyond its anti-hyperglycaemic effects, remain largely unclear. Metformin is reported to reduce the long-term complications of diabetes, including cardiovascular fibrosis...
2.
Riccetti M, Ushakumary M, Waltamath M, Green J, Snowball J, Dautel S, et al.
JCI Insight . 2022 Feb; 7(5). PMID: 35113810
Infants born prematurely worldwide have up to a 50% chance of developing bronchopulmonary dysplasia (BPD), a clinical morbidity characterized by dysregulated lung alveolarization and microvascular development. It is known that...
3.
Titus A, Venugopal H, Ushakumary M, Wang M, Cowling R, Lakatta E, et al.
Int J Mol Sci . 2021 Sep; 22(17). PMID: 34502259
This study probed the largely unexplored regulation and role of fibronectin in Angiotensin II-stimulated cardiac fibroblasts. Using gene knockdown and overexpression approaches, Western blotting, and promoter pull-down assay, we show...
4.
Ushakumary M, Riccetti M, Perl A
Stem Cells Transl Med . 2021 Feb; 10(7):1021-1032. PMID: 33624948
Developing, regenerating, and repairing a lung all require interstitial resident fibroblasts (iReFs) to direct the behavior of the epithelial stem cell niche. During lung development, distal lung fibroblasts, in the...
5.
Ushakumary M, Wang M, V H, Titus A, Zhang J, Liu L, et al.
PLoS One . 2019 Dec; 14(12):e0225911. PMID: 31805124
Collagen accumulation and remodeling in the vascular wall is a cardinal feature of vascular fibrosis that exacerbates the complications of hypertension, aging, diabetes and atherosclerosis. With no specific therapy available...