Menotti Calvani
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Explore the profile of Menotti Calvani including associated specialties, affiliations and a list of published articles.
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68
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2231
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Recent Articles
1.
De Lorenzo A, Soldati L, Sarlo F, Calvani M, Lorenzo N, Di Renzo L
World J Gastroenterol
. 2016 Jan;
22(2):681-703.
PMID: 26811617
Obesity plays relevant pathophysiological role in the development of health problems, arising as result of complex interaction of genetic, nutritional, and metabolic factors. Due to the role of adipose tissue...
2.
Onofrj M, Ciccocioppo F, Varanese S, Di Muzio A, Calvani M, Chiechio S, et al.
Expert Rev Neurother
. 2013 Aug;
13(8):925-36.
PMID: 23965166
Acetyl-L-carnitine (ALC) is a molecule derived from acetylation of carnitine in the mitochondria. Carnitine acetylation enables the function of CoA and facilitates elimination of oxidative products. Beyond this metabolic activity,...
3.
Pacilli A, Calienni M, Margarucci S, dApolito M, Petillo O, Rocchi L, et al.
J Natl Cancer Inst
. 2013 Mar;
105(7):489-98.
PMID: 23486551
Background: The metabolic alterations of cancer cells represent an opportunity for developing selective antineoplastic treatments. We investigated the therapeutic potential of ST1326, an inhibitor of carnitine-palmitoyl transferase 1A (CPT1A), the...
4.
Notarnicola M, Tutino V, Calvani M, Lorusso D, Guerra V, Caruso M
J Gastrointest Cancer
. 2011 Jul;
43(3):508-11.
PMID: 21727995
Purpose: Fatty acid synthase is a common phenotype to various human cancers including those of prostate, colon, lung, endometrium, and stomach. Increased fatty acid synthase levels have been detected in...
5.
Musicco C, Capelli V, Pesce V, Timperio A, Calvani M, Mosconi L, et al.
J Proteomics
. 2011 Jun;
74(11):2536-47.
PMID: 21672642
Oxidative stress has a central role in aging and in several age-linked diseases such as neurodegenerative diseases, diabetes and cancer. Mitochondria, as the main cellular source and target of reactive...
6.
Palermo V, Falcone C, Calvani M, Mazzoni C
Aging Cell
. 2010 Jun;
9(4):570-9.
PMID: 20550520
In this work we report that carnitines, in particular acetyl-l-carnitine (ALC), are able to prolong the chronological aging of yeast cells during the stationary phase. Lifespan extension is significantly reduced...
7.
Cassano P, Fluck M, Sciancalepore A, Pesce V, Calvani M, Hoppeler H, et al.
Biofactors
. 2010 Jan;
36(1):70-7.
PMID: 20091799
The effect of acetyl-L-carnitine (ALCAR) supplementation to 3-month-old rats in normal-loading and unloading conditions has been here investigated by a combined morphological, biochemical and transcriptional approach to test whether ALCAR...
8.
Musicco C, Capelli V, Pesce V, Timperio A, Calvani M, Mosconi L, et al.
Biochim Biophys Acta
. 2009 Mar;
1787(7):890-6.
PMID: 19272351
Overoxidation and subsequent inactivation of Peroxiredoxin III (PrxIII), a mitochondrial H(2)O(2) scavenging enzyme, have been reported in oxidative stress conditions. No data are available in the literature about the presence...
9.
Janiri L, Martinotti G, Tonioni F, Ghelardini C, Nicolai R, Galeotti N, et al.
Clin Neuropharmacol
. 2008 Nov;
32(1):35-40.
PMID: 18978503
Introduction: This study was designed to determine the short-term effect of acetyl-l-carnitine (ALC) on symptoms of withdrawal in opiate-dependent subjects and animals and, in particular, on pain, given the efficacy...
10.
Epis R, Marcello E, Gardoni F, Longhi A, Calvani M, Iannuccelli M, et al.
Eur J Pharmacol
. 2008 Sep;
597(1-3):51-6.
PMID: 18801359
Alzheimer Disease is the most common chronic neurodegenerative disorder associated with aging. Nevertheless, its pharmacological therapy is still an unresolved issue. In double-blind controlled studies, acetyl-L-carnitine (ALC) demonstrated beneficial effects...