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Mengdan Tao

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Articles 12
Citations 182
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Recent Articles
1.
Yang Y, Yu T, Tao M, Wang Y, Yao X, Zhu C, et al.
Polymers (Basel) . 2025 Feb; 17(3). PMID: 39940505
Skin tissue engineering scaffolds should possess key properties such as porosity, degradability, durability, and biocompatibility to effectively facilitate skin cell adhesion and growth. In this study, recombinant human collagen (RHC)...
2.
Tao M, Wang C, Zheng Z, Gao W, Chen Q, Xu M, et al.
Ecotoxicol Environ Saf . 2024 Sep; 285:117063. PMID: 39299213
Nanoplastics are ubiquitous in our daily lives, raising concerns about their potential impact on the human brain. Many studies reported that nanoplastics permeate the blood-brain barrier and influence cellular processes...
3.
Xu L, Ding H, Wu S, Xiong N, Hong Y, Zhu W, et al.
ACS Nano . 2024 Sep; PMID: 39270300
Brain organoids are widely used to model brain development and diseases. However, a major challenge in their application is the insufficient supply of oxygen and nutrients to the core region,...
4.
Wu S, Hong Y, Chu C, Gan Y, Li X, Tao M, et al.
Proc Natl Acad Sci U S A . 2024 May; 121(22):e2316176121. PMID: 38771878
The striato-nigral (Str-SN) circuit is composed of medium spiny neuronal projections that are mainly sent from the striatum to the midbrain substantial nigra (SN), which is essential for regulating motor...
5.
Zhang Z, Wang R, Zhou H, Wu D, Cao Y, Zhang C, et al.
Cell Mol Life Sci . 2024 Mar; 81(1):128. PMID: 38472451
Epigenetic dysregulation that leads to alterations in gene expression and is suggested to be one of the key pathophysiological factors of Parkinson's disease (PD). Here, we found that α-synuclein preformed...
6.
Zhang Y, Cao F, Xu M, Li X, Tao M, Wu S, et al.
ACS Appl Mater Interfaces . 2023 Dec; 15(50):58230-58240. PMID: 38063343
Despite the fact that human neural cell models have played significant roles in both research and cell replacement therapies for neurological diseases, the existing techniques for obtaining neurons from human...
7.
Zheng Z, Han L, Li Y, Chen Z, Yang W, Liu C, et al.
Biochim Biophys Acta Mol Cell Res . 2023 May; 1870(6):119487. PMID: 37211156
Mitochondrial protein homeostasis is fine-tuned by diverse physiological processes such as mitochondria-associated degradation (MAD), which is regulated by valosin-containing protein (VCP) and its cofactors. As a cofactor of VCP, the...
8.
Lu K, Hong Y, Tao M, Shen L, Zheng Z, Fang K, et al.
EMBO Mol Med . 2022 Nov; 15(1):e16364. PMID: 36373384
Major depressive disorder with suicide behavior (sMDD) is a server mood disorder, bringing tremendous burden to family and society. Although reduced gamma amino butyric acid (GABA) level has been observed...
9.
Zhu W, Tao M, Hong Y, Wu S, Chu C, Zheng Z, et al.
Chem Sci . 2022 Jun; 13(21):6217-6223. PMID: 35733907
Electrochemical cytometry based on nano-tip microelectrodes was used to quantify the vesicular storage at the single-cell level in human neurons and midbrain organoids which acted as disease models of young-onset...
10.
Tang X, Wu S, Wang D, Chu C, Hong Y, Tao M, et al.
Signal Transduct Target Ther . 2022 May; 7(1):168. PMID: 35610212
Organoids are three-dimensional (3D) miniature structures cultured in vitro produced from either human pluripotent stem cells (hPSCs) or adult stem cells (AdSCs) derived from healthy individuals or patients that recapitulate...