Melissa G Metcalf
Overview
Explore the profile of Melissa G Metcalf including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
6
Citations
188
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Metcalf M, Monshietehadi S, Sahay A, Durieux J, Frakes A, Velichkovska M, et al.
iScience
. 2024 Mar;
27(4):109354.
PMID: 38500817
Glia are the protectors of the nervous system, providing neurons with support and protection from cytotoxic insults. We previously discovered that four astrocyte-like glia can regulate organismal proteostasis and longevity...
2.
Bonheur M, Swartz K, Metcalf M, Wen X, Zhukovskaya A, Mehta A, et al.
Nat Neurosci
. 2023 Jun;
26(7):1295-1307.
PMID: 37308660
Neural activity is modulated over different timescales encompassing subseconds to hours, reflecting changes in external environment, internal state and behavior. Using Drosophila as a model, we developed a rapid and...
3.
Metcalf M, Higuchi-Sanabria R, Garcia G, Tsui C, Dillin A
Sci Adv
. 2020 Aug;
6(29):eabb9614.
PMID: 32832649
The endoplasmic reticulum (ER) is commonly referred to as the factory of the cell, as it is responsible for a large amount of protein and lipid synthesis. As a membrane-bound...
4.
Bar-Ziv R, Frakes A, Higuchi-Sanabria R, Bolas T, Frankino P, Gildea H, et al.
J Vis Exp
. 2020 Jun;
(159).
PMID: 32510480
Organisms are often exposed to fluctuating environments and changes in intracellular homeostasis, which can have detrimental effects on their proteome and physiology. Thus, organisms have evolved targeted and specific stress...
5.
Frakes A, Metcalf M, Tronnes S, Bar-Ziv R, Durieux J, Gildea H, et al.
Science
. 2020 Jan;
367(6476):436-440.
PMID: 31974253
The ability of the nervous system to sense cellular stress and coordinate protein homeostasis is essential for organismal health. Unfortunately, stress responses that mitigate disturbances in proteostasis, such as the...
6.
Daniele J, Higuchi-Sanabria R, Durieux J, Monshietehadi S, Ramachandran V, Tronnes S, et al.
Sci Adv
. 2020 Jan;
6(1):eaaz1441.
PMID: 31911951
Longevity is dictated by a combination of environmental and genetic factors. One of the key mechanisms to regulate life-span extension is the induction of protein chaperones for protein homeostasis. Ectopic...