Melike Cokol-Cakmak
Overview
Explore the profile of Melike Cokol-Cakmak including associated specialties, affiliations and a list of published articles.
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4
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87
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Recent Articles
1.
Cokol-Cakmak M, Cetiner S, Erdem N, Bakan F, Cokol M
PLoS One
. 2020 Jul;
15(7):e0235929.
PMID: 32645104
Combinations of three or more drugs are routinely used in various medical fields such as clinical oncology and infectious diseases to prevent resistance or to achieve synergistic therapeutic benefits. The...
2.
Cokol-Cakmak M, Cokol M
Methods Mol Biol
. 2019 Mar;
1939:3-9.
PMID: 30848453
Drugs may have synergistic or antagonistic interactions when combined. Checkerboard assays, where two drugs are combined in many doses, allow sensitive measurement of drug interactions. Here, we describe a protocol...
3.
Cokol-Cakmak M, Bakan F, Cetiner S, Cokol M
J Vis Exp
. 2018 Jul;
(136).
PMID: 29985330
A synergistic drug combination has a higher efficacy compared to the effects of individual drugs. Checkerboard assays, where drugs are combined in many doses, allow sensitive measurement of drug interactions....
4.
Chandrasekaran S, Cokol-Cakmak M, Sahin N, Yilancioglu K, Kazan H, Collins J, et al.
Mol Syst Biol
. 2016 May;
12(5):872.
PMID: 27222539
Combination antibiotic therapies are being increasingly used in the clinic to enhance potency and counter drug resistance. However, the large search space of candidate drugs and dosage regimes makes the...