Melanie Laurin
Overview
Explore the profile of Melanie Laurin including associated specialties, affiliations and a list of published articles.
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14
Citations
460
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Recent Articles
1.
Kalyanakrishnan K, Beaudin A, Jette A, Ghezelbash S, Hotea D, Chen J, et al.
bioRxiv
. 2024 Sep;
PMID: 39314354
During embryogenesis, cells arrange into precise patterns that enable tissues and organs to develop specialized functions. Despite its critical importance, the molecular choreography behind these collective cellular behaviors remains elusive,...
2.
Gamblin C, Alende C, Corriveau F, Jette A, Parent-Prevost F, Biehler C, et al.
J Cell Sci
. 2024 Apr;
137(10).
PMID: 38682269
The subcellular distribution of the polarity protein Yurt (Yrt) is subjected to a spatio-temporal regulation in Drosophila melanogaster embryonic epithelia. After cellularization, Yrt binds to the lateral membrane of ectodermal...
3.
Yang Y, Gomez N, Infarinato N, Adam R, Sribour M, Baek I, et al.
Nat Cell Biol
. 2023 Jul;
25(8):1185-1195.
PMID: 37488435
During development, progenitors simultaneously activate one lineage while silencing another, a feature highly regulated in adult stem cells but derailed in cancers. Equipped to bind cognate motifs in closed chromatin,...
4.
Pecora A, Laprise J, Dahmene M, Laurin M
Cancers (Basel)
. 2021 Sep;
13(17).
PMID: 34503171
Skin cancers are the most common cancers worldwide. Among them, melanoma, basal cell carcinoma of the skin and cutaneous squamous cell carcinoma are the three major subtypes. These cancers are...
5.
Dahmene M, Quirion L, Laurin M
Cells
. 2020 Jun;
9(6).
PMID: 32526908
Since their discovery, Rho GTPases have emerged as key regulators of cytoskeletal dynamics. In humans, there are 20 Rho GTPases and more than 150 regulators that belong to the RhoGEF,...
6.
Laurin M, Gomez N, Levorse J, Sendoel A, Sribour M, Fuchs E
Elife
. 2019 Sep;
8.
PMID: 31556874
During mammalian embryogenesis, extensive cellular remodeling is needed for tissue morphogenesis. As effectors of cytoskeletal dynamics, Rho GTPases and their regulators are likely involved, but their daunting complexity has hindered...
7.
Laurin M, Cote J
Genes Dev
. 2014 Mar;
28(6):533-47.
PMID: 24637113
Rho GTPases play key regulatory roles in many aspects of embryonic development, regulating processes such as differentiation, proliferation, morphogenesis, and migration. Two families of guanine nucleotide exchange factors (GEFs) found...
8.
Laurin M, Dumouchel A, Fukui Y, Cote J
Small GTPases
. 2013 Dec;
4(4):221-30.
PMID: 24365888
Podocytes are specialized kidney cells that form the kidney filtration barrier through the connection of their foot processes. Nephrin and Neph family transmembrane molecules at the surface of podocytes interconnect...
9.
Laurin M, Huber J, Pelletier A, Houalla T, Park M, Fukui Y, et al.
Proc Natl Acad Sci U S A
. 2013 Apr;
110(18):7434-9.
PMID: 23592719
Progression of solid tumors to the metastatic stage is accountable for the majority of cancer-related deaths. Further understanding of the molecular mechanisms governing metastasis is essential for the development of...
10.
Vives V, Laurin M, Cres G, Larrousse P, Morichaud Z, Noel D, et al.
J Bone Miner Res
. 2011 May;
26(5):1099-110.
PMID: 21542010
Osteoporosis, which results from excessive bone resorption by osteoclasts, is the major cause of morbidity for elder people. Identification of clinically relevant regulators is needed to develop novel therapeutic strategies....