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Melanie Hart

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Articles 16
Citations 320
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Recent Articles
1.
Brown R, Thomas-Black G, Garcia-Moreno H, Chou M, Fleszar Z, Zandi M, et al.
J Neurol . 2025 Feb; 272(3):222. PMID: 39985693
Background: The interpretation of antibodies to glutamic acid decarboxylase 65 (GAD-Abs) in neurological practice is challenging. GAD-Abs are not considered directly pathogenic and immunotherapy guidelines are lacking. Methods: We undertook...
2.
Schuldt A, Bern H, Hart M, Gompels M, Winston A, Clarke A, et al.
Viruses . 2024 Jan; 16(1). PMID: 38275937
The aim of this study is to identify the factors associated with peripheral neuropathy and to explore neurofilament light chain (NfL) as a biomarker for peripheral neuropathy (PN) in effectively...
3.
Gibson L, Pollak T, Hart M, Heslegrave A, Hye A, Church A, et al.
J Neuropsychiatry Clin Neurosci . 2023 Jan; 35(3):236-243. PMID: 36710627
Objective: -methyl-d-aspartate receptor (NMDAR) encephalitis is an autoantibody-mediated neurological syndrome with prominent cognitive and neuropsychiatric symptoms. The clinical relevance of NMDAR antibodies outside the context of encephalitis was assessed in...
4.
Delaby C, Teunissen C, Blennow K, Alcolea D, Arisi I, Amar E, et al.
Alzheimers Dement . 2021 Dec; 18(10):1868-1879. PMID: 34936194
Introduction: The current practice of quantifying cerebrospinal fluid (CSF) biomarkers as an aid in the diagnosis of Alzheimer's disease (AD) varies from center to center. For a same biochemical profile,...
5.
Benjamin L, Paterson R, Moll R, Pericleous C, Brown R, Mehta P, et al.
EClinicalMedicine . 2021 Aug; 39:101070. PMID: 34401683
Background: A high prevalence of antiphospholipid antibodies has been reported in case series of patients with neurological manifestations and COVID-19; however, the pathogenicity of antiphospholipid antibodies in COVID-19 neurology remains...
6.
Abrol E, Coutinho E, Chou M, Hart M, Vincent A, Howard R, et al.
Rheumatology (Oxford) . 2021 Feb; 60(12):5620-5629. PMID: 33629101
Objectives: The long-term outcome of psychosis in association with systemic lupus erythematosus (SLE) has been insufficiently characterised. We used a specialist centre cohort of patients with SLE and psychosis to...
7.
Keshavan A, Wellington H, Chen Z, Khatun A, Chapman M, Hart M, et al.
Alzheimers Dement (Amst) . 2021 Feb; 13(1):e12131. PMID: 33598527
Introduction: We assessed the concordance of cerebrospinal fluid (CSF) amyloid beta (Aβ) and tau measured on the fully automated Lumipulse platform with pre-symptomatic Alzheimer's disease (AD) pathology on amyloid positron...
8.
Keshavan A, Wellington H, Chen Z, Khatun A, Chapman M, Hart M, et al.
Alzheimers Dement (Amst) . 2020 Oct; 12(1):e12097. PMID: 32999915
Introduction: We assessed the concordance of cerebrospinal fluid (CSF) amyloid beta (Aβ) and tau measured on the fully automated Lumipulse platform with pre-symptomatic Alzheimer's disease (AD) pathology on amyloid positron...
9.
Wijesinghe H, Galappatthy P, de Silva R, Seneviratne S, Saravanamuttu U, Udagama P, et al.
BMC Musculoskelet Disord . 2017 Jul; 18(1):310. PMID: 28724365
Background: The standard dose of rituximab used in rheumatoid arthritis (RA) is 1000 mg but recent studies have shown that low dose (500 mg) is also effective. Efficacy of low...
10.
Seeger T, Hart M, Patarroyo M, Rolauffs B, Aicher W, Klein G
PLoS One . 2015 Sep; 10(9):e0137419. PMID: 26406476
Multipotent mesenchymal stromal cells (MSCs) are well known for their tri-lineage potential and ability to differentiate in vitro into osteogenic, chondrogenic or adipogenic lineages. By selecting appropriate conditions MSCs can...