Alpha 2.0
Login Register
» Authors » Melania Pintilie

Melania Pintilie

Explore the profile of Melania Pintilie including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 197
Citations 7167
Followers 0
Related Specialties
Oncology
Radiology
Pathology
Top 10 Co-Authors
Ming-Sound Tsao
Michael Milosevic
Frances A Shepherd
Anthony Fyles
Richard P Hill
Igor Jurisica
Jenna Sykes
Fei-Fei Liu
Geoffrey Liu
Robert G Bristow
Published In
Clin Cancer Res
Int J Radiat Oncol Biol Phys
Radiother Oncol
J Clin Oncol
Cancer
Affiliations
Soon will be listed here.
Recent Articles
11.
Predicting response and toxicity to PD-1 inhibition using serum autoantibodies identified from immuno-mass spectrometry
Music M, Iafolla M, Soosaipillai A, Batruch I, Prassas I, Pintilie M, et al.
F1000Res . 2020 Dec; 9:337. PMID: 33299547
Validated biomarkers are needed to identify patients at increased risk of immune-related adverse events (irAEs) to immune checkpoint blockade (ICB). Antibodies directed against endogenous antigens can change after exposure to...
12.
Circulating miR-16-5p, miR-92a-3p, and miR-451a in Plasma from Lung Cancer Patients: Potential Application in Early Detection and a Regulatory Role in Tumorigenesis Pathways
Reis P, Drigo S, Carvalho R, Lopez Lapa R, Felix T, Patel D, et al.
Cancers (Basel) . 2020 Jul; 12(8). PMID: 32726984
Background: Micro(mi)RNAs, potent gene expression regulators associated with tumorigenesis, are stable, abundant circulating molecules, and detectable in plasma. Thus, miRNAs could potentially be useful in early lung cancer detection. We...
13.
Intratumoral heterogeneity and hypoxia gene expression signatures: Is a single biopsy adequate?
Lukovic J, Han K, Pintilie M, Chaudary N, Hill R, Fyles A, et al.
Clin Transl Radiat Oncol . 2019 Oct; 19:110-115. PMID: 31650046
Background And Purpose: Gene expression signatures are often used to identify hypoxic tumors. However, intratumoral heterogeneity raises concern that multiple biopsies may be necessary to assess global hypoxia status. The...
14.
Evaluation of Lymphadenopathy and Suspected Lymphoma in a Lymphoma Rapid Diagnosis Clinic
Nixon S, Bezverbnaya K, Maganti M, Gullane P, Reedijk M, Kuruvilla J, et al.
JCO Oncol Pract . 2019 Oct; 16(1):e29-e36. PMID: 31573831
Purpose: Lymphomas often present a diagnostic challenge, and for some a delay in diagnosis can negatively influence outcomes of therapy. We established a nurse practitioner-led lymphoma rapid diagnosis clinic (LRDC)...
15.
Correction: Targeting CXCL12/CXCR4 and myeloid cells to improve the therapeutic ratio in patient-derived cervical cancer models treated with radio-chemotherapy
Lecavalier-Barsoum M, Chaudary N, Han K, Pintilie M, Hill R, Milosevic M
Br J Cancer . 2019 Aug; 121(7):626. PMID: 31399696
Since the publication of this paper, the authors have reported that an incorrect version of Figure 1 was presented. The correct version of Figure 1 is provided.An amendment to this...
16.
Anaplastic lymphoma kinase 5A4 immunohistochemistry as a diagnostic assay in lung cancer: A Canadian reference testing center's results in population-based reflex testing
Fiset P, Labbe C, Young K, Craddock K, Smith A, Tanguay J, et al.
Cancer . 2019 Aug; 125(22):4043-4051. PMID: 31390053
Background: The presence of anaplastic lymphoma kinase (ALK) rearrangement predicts response to ALK tyrosine kinase inhibitor (TKI) therapy. Fluorescence in situ hybridization (FISH) was the initial reference standard to detect...
17.
Somatic Alteration Burden Involving Non-Cancer Genes Predicts Prognosis in Early-Stage Non-Small Cell Lung Cancer
Wang D, Pham N, Freeman T, Raghavan V, Navab R, Chang J, et al.
Cancers (Basel) . 2019 Jul; 11(7). PMID: 31330989
The burden of somatic mutations and neoantigens has been associated with improved survival in cancer treated with immunotherapies, especially non-small cell lung cancer (NSCLC). However, there is uncertainty about their...
18.
HPV-independent Vulvar Squamous Cell Carcinoma is Associated With Significantly Worse Prognosis Compared With HPV-associated Tumors
Allo G, Yap M, Cuartero J, Milosevic M, Ferguson S, MacKay H, et al.
Int J Gynecol Pathol . 2019 Jul; 39(4):391-399. PMID: 31274700
Vulvar squamous cell carcinomas (VSCC) represent the most common carcinoma of the female external genitalia, with increasing incidence. Although high-risk human papillomavirus (HPV) infection has long been implicated in the...
19.
Targeting CXCL12/CXCR4 and myeloid cells to improve the therapeutic ratio in patient-derived cervical cancer models treated with radio-chemotherapy
Lecavalier-Barsoum M, Chaudary N, Han K, Pintilie M, Hill R, Milosevic M
Br J Cancer . 2019 Jun; 121(3):249-256. PMID: 31239542
Background: The CXCL12/CXCR4 chemokine pathway is involved in cervical cancer pathogenesis and radiation treatment (RT) response. We previously reported that radiochemotherapy (RTCT) and concurrent administration of the CXCR4 inhibitor plerixafor...
20.
Repeatability and reproducibility of MRI-based radiomic features in cervical cancer
Fiset S, Welch M, Weiss J, Pintilie M, Conway J, Milosevic M, et al.
Radiother Oncol . 2019 Apr; 135:107-114. PMID: 31015155
Purpose: The aims of this study are to evaluate the stability of radiomic features from T2-weighted MRI of cervical cancer in three ways: (1) repeatability via test-retest; (2) reproducibility between...