Mel Greaves
Overview
Explore the profile of Mel Greaves including associated specialties, affiliations and a list of published articles.
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Articles
103
Citations
11607
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Recent Articles
1.
Mansur M, Greaves M
BMC Ecol Evol
. 2023 Sep;
23(1):54.
PMID: 37743495
Cancer cell populations evolve by a stepwise process involving natural selection of the fittest variants within a tissue ecosystem context and as modified by therapy. Genomic scrutiny of patient samples...
2.
Mansur M, deSouza N, Natrajan R, Abegglen L, Schiffman J, Greaves M
Nat Ecol Evol
. 2023 Aug;
7(11):1761-1770.
PMID: 37620552
The emergence of drug-resistant cells, most of which have a mutated TP53 gene, prevents curative treatment in most advanced and common metastatic cancers of adults. Yet, a few, rarer malignancies,...
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Pombo-de-Oliveira M, Petridou E, Karalexi M, Junqueira M, Braga F, Bouzas L, et al.
Cancer Epidemiol Biomarkers Prev
. 2022 Dec;
32(3):371-379.
PMID: 36525650
Background: Childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL) has been associated with early-life exposures, including birth by cesarean section (C-section), and a deficit of social exposure (first child). These exposures...
5.
deSouza N, Choudhury A, Greaves M, OConnor J, Hoskin P
Front Oncol
. 2022 Nov;
12:1020907.
PMID: 36439503
No abstract available.
6.
Ermini L, Francis J, Rosa G, Rose A, Ning J, Greaves M, et al.
Evol Med Public Health
. 2021 Nov;
9(1):311-321.
PMID: 34754452
Background And Objectives: Several hundred inherited genetic variants or SNPs that alter the risk of cancer have been identified through genome-wide association studies. In populations of European ancestry, these variants...
7.
Turati V, Guerra-Assuncao J, Potter N, Gupta R, Ecker S, Daneviciute A, et al.
Nat Cancer
. 2021 Nov;
2(8):835-852.
PMID: 34734190
Comparison of intratumor genetic heterogeneity in cancer at diagnosis and relapse suggests that chemotherapy induces bottleneck selection of subclonal genotypes. However, evolutionary events subsequent to chemotherapy could also explain changes...
8.
Mangum D, Meyer J, Mason C, Shams S, Maese L, Gardiner J, et al.
JAMA Oncol
. 2021 Aug;
7(10):1521-1528.
PMID: 34410295
Importance: Alterations in the IKZF1 gene drive B-cell acute lymphoblastic leukemia (B-ALL) but are not routinely used to stratify patients by risk because of inconsistent associations with outcomes. We describe...
9.
Greaves M, Cazzaniga V, Ford A
Leukemia
. 2021 Apr;
35(5):1258-1264.
PMID: 33833382
No abstract available.
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