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Meiwan Chen

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Articles 187
Citations 3335
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Recent Articles
1.
Yin Y, Wong K, Wen L, Chen M
Adv Healthc Mater . 2025 Feb; :e2404485. PMID: 39988848
Photodynamic therapy (PDT) and photothermal therapy (PTT) offer the advantages of precise temporal and spatial selectivity in cancer treatment, minimizing damage to normal cells while effectively eliminating tumor cells. However,...
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Chen R, Wen L, Guo F, He J, Wong K, Chen M
J Control Release . 2025 Jan; 379:866-878. PMID: 39842724
Nanomedicine-driven ferroptosis has emerged as a promising tumor treatment strategy through delivering exogenous iron and aggravating the lethal accumulation of lipid peroxides (LPO). However, the compensatory mechanisms of ferroptosis defense...
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Zhang Y, Zhai S, Qin S, Chen Y, Chen K, Huang Z, et al.
Bioeng Transl Med . 2025 Jan; 10(1):e10709. PMID: 39801759
The major histocompatibility complex class I (MHCI) trafficking signal (MITD) plays a pivotal role in enhancing the efficacy of mRNA vaccines. However, there was a lack of research investigating its...
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Yang S, Chen R, Wu Y, Song X, Peng X, Chen M
Acta Biomater . 2024 Dec; 192():340-352. PMID: 39657865
Latent membrane protein 2 (LMP2), which is an important protein of Epstein-Barr virus (EBV) in the latent phase to mediate metastasis and recurrence, has shown great potential as a targeting...
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Wang J, Lv X, Li Y, Wu H, Chen M, Yu H, et al.
J Control Release . 2024 Nov; 377:606-618. PMID: 39608456
Intestinal mucosal barrier loss is responsible for the chronic and recurrent ulcerative colitis. Myosin light chain kinase (MLCK) is a potential therapeutic target of the intestinal mucosal barrier dysfunction. Here,...
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Chen F, Huang H, Zhang F, Wang R, Wang L, Chang Z, et al.
Adv Mater . 2024 Nov; 37(4):e2413385. PMID: 39499050
Photocatalytic therapy for hypoxic tumors often suffers from inefficiencies due to its dependence on oxygen and the risk of uncontrolled activation. Inspired by the oxygen-independent and precisely regulated photocatalytic functions...
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Liu R, Sun Z, Wang S, Liu X, Man Y, Chen M, et al.
Aging (Albany NY) . 2024 Sep; 16(18):12574-12592. PMID: 39237304
Anti-inflammatory and antioxidant effects play crucial roles in the recovery of benign prostatic hyperplasia (BPH). Wenshenqianlie (WSQL) capsule, a typical traditional Chinese medicine formulation combining 14 Chinese herbs, has been...
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Mo H, Liu J, Su Z, Zhao D, Ma Y, Zhang K, et al.
Eur J Med Chem . 2024 Aug; 277():116765. PMID: 39146833
Conventional chemotherapy, especially with natural anticancer drugs, usually suffers from poor bioavailability and low tumor accumulation. To address these limitations, we developed a novel approach for modifying natural products in...
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Liu Z, Huang J, Fang D, Feng B, Luo J, Lei P, et al.
Mater Today Bio . 2024 Jul; 27:101153. PMID: 39081462
The advantage of low-temperature forming through direct ink writing (DIW) 3D printing is becoming a strategy for the construction of innovative drug delivery systems (DDSs). Optimization of the complex formulation,...