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Meinolf Blaszkewicz

Explore the profile of Meinolf Blaszkewicz including associated specialties, affiliations and a list of published articles. Areas
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Articles 110
Citations 1144
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Recent Articles
1.
Kadhum T, Selinski S, Blaszkewicz M, Reinders J, Roth E, Volkert F, et al.
EXCLI J . 2023 Sep; 22:867-879. PMID: 37720238
Urinary bladder cancer, a smoking and occupation related disease, was subject of several genome-wide association studies (GWAS). However, studies on the course of the disease based on GWAS findings differentiating...
2.
Kleinbeck S, Schaper M, Pacharra M, Lehmann M, Golka K, Blaszkewicz M, et al.
Arch Toxicol . 2020 Mar; 94(5):1687-1701. PMID: 32185413
Sensory irritation is an acute adverse effect caused by chemicals that stimulate chemoreceptors of the upper respiratory tract or the mucous membranes of the outer eye. The avoidance of this...
3.
Birch Kristensen E, Yakimov V, Bjorn-Mortensen K, Soborg B, Koch A, Andersson M, et al.
EXCLI J . 2018 Dec; 17:1043-1053. PMID: 30564082
-acetyltransferase 2 (NAT2) is the main enzyme metabolizing isoniazid and genotype-based treatment has been studied for years without becoming common practice. To investigate whether genotype-based isoniazid treatment is feasible in...
4.
Selinski S, Blaszkewicz M, Ickstadt K, Gerullis H, Otto T, Roth E, et al.
Carcinogenesis . 2017 Oct; 38(12):1167-1179. PMID: 29028944
Little is known whether genetic variants identified in genome-wide association studies interact to increase bladder cancer risk. Recently, we identified two- and three-variant combinations associated with a particular increase of...
5.
Michael G, Thier R, Blaszkewicz M, Selinski S, Golka K
Methods Mol Biol . 2017 Sep; 1655:77-96. PMID: 28889379
N-Acetyltransferase 2 (NAT2) genotyping by PCR and RFLP-based methods provides information on seven single nucleotide polymorphisms (SNPs) without deriving the chromosomal phase (haplotype). So genotyping results must be processed to...
6.
Kuhn C, Lehmann M, Kress A, Truss M, Hermes M, Blaszkewicz M, et al.
J Toxicol Environ Health A . 2017 Jul; 80(7-8):411-416. PMID: 28696914
The gold standard of saving fresh tissue in liquid nitrogen has some serious disadvantages in that this process is not available in daily medical routine practices even in many tumor...
7.
Hohne S, Gerullis H, Blaszkewicz M, Selinski S, Hengstler J, Otto T, et al.
J Toxicol Environ Health A . 2017 Jul; 80(7-8):417-422. PMID: 28696911
In a large bladder cancer study in the greater Berlin area with 425 cases and 343 controls, the haplotype N-acetyltransferase 1*10 (NAT1*10) was associated with a decreased bladder cancer risk....
8.
Ebbinghaus D, Banfi G, Selinski S, Blaszkewicz M, Burger H, Hengstler J, et al.
J Toxicol Environ Health A . 2017 Jul; 80(7-8):423-429. PMID: 28696897
Polymorphic xenobiotic metabolizing enzymes such as N-acetyltransferase 2 (NAT2) or glutathione S-transferase M1 (GSTM1) are known to modulate bladder cancer risk. As no apparent data were available from Hungary, a...
9.
Krech E, Selinski S, Blaszkewicz M, Burger H, Kadhum T, Hengstler J, et al.
J Toxicol Environ Health A . 2017 Jul; 80(7-8):430-438. PMID: 28696895
This study was performed to investigate the frequency of bladder cancer in patients with an occupational history such as underground hard coal mining and/or painting after the structural change in...
10.
Lukas C, Selinski S, Prager H, Blaszkewicz M, Hengstler J, Golka K
J Toxicol Environ Health A . 2017 Jul; 80(7-8):439-452. PMID: 28696839
Approximately 7% of all bladder cancer cases in males are associated with occupation. The question arises whether the use of genome-wide association studies was able to identify bladder cancer risk...