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Mei Chin Lee

Explore the profile of Mei Chin Lee including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 260
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Recent Articles
1.
Muralidharan S, Lee J, Lim Y, Muthiah M, Tan E, Demicioglu D, et al.
Metabolism . 2024 Nov; 162:156063. PMID: 39522592
Background & Aims: Metabolic dysfunction-associated steatotic liver disease (MASLD) represents a spectrum of pathologies ranging from simple steatosis to steatohepatitis, fibrosis and cirrhosis. Patients with metabolic associated steatohepatitis (MASH) with...
2.
Li Z, Wang Z, Lee M, Zenkel M, Peh E, Ozaki M, et al.
JAMA . 2021 Feb; 325(8):753-764. PMID: 33620406
Importance: Exfoliation syndrome is a systemic disorder characterized by progressive accumulation of abnormal fibrillar protein aggregates manifesting clinically in the anterior chamber of the eye. This disorder is the most...
3.
Yonova-Doing E, Zhao W, Igo Jr R, Wang C, Sundaresan P, Lee K, et al.
Commun Biol . 2020 Dec; 3(1):755. PMID: 33311586
Nuclear cataract is the most common type of age-related cataract and a leading cause of blindness worldwide. Age-related nuclear cataract is heritable (h = 0.48), but little is known about...
4.
Aung T, Ozaki M, Lee M, Schlotzer-Schrehardt U, Thorleifsson G, Mizoguchi T, et al.
Nat Genet . 2017 May; 49(7):993-1004. PMID: 28553957
Exfoliation syndrome (XFS) is the most common known risk factor for secondary glaucoma and a major cause of blindness worldwide. Variants in two genes, LOXL1 and CACNA1A, have previously been...
5.
Aung T, Ozaki M, Mizoguchi T, Allingham R, Li Z, Haripriya A, et al.
Nat Genet . 2015 May; 47(6):689. PMID: 26018902
No abstract available.
6.
Li Z, Allingham R, Nakano M, Jia L, Chen Y, Ikeda Y, et al.
Hum Mol Genet . 2015 Apr; 24(13):3880-92. PMID: 25861811
Primary open angle glaucoma (POAG), a major cause of blindness worldwide, is a complex disease with a significant genetic contribution. We performed Exome Array (Illumina) analysis on 3504 POAG cases...
7.
Aung T, Ozaki M, Mizoguchi T, Allingham R, Li Z, Haripriya A, et al.
Nat Genet . 2015 Feb; 47(4):387-92. PMID: 25706626
Exfoliation syndrome (XFS) is the most common recognizable cause of open-angle glaucoma worldwide. To better understand the etiology of XFS, we conducted a genome-wide association study (GWAS) of 1,484 cases...
8.
Lee M, Chan A, Goh S, Hilmy M, Nongpiur M, Hong W, et al.
Invest Ophthalmol Vis Sci . 2014 May; 55(6):3833-41. PMID: 24801512
Purpose: The role of the recently identified primary angle closure glaucoma (PACG) susceptibility gene, pleckstrin homology domain containing, family A member 7 (PLEKHA7), in PACG is unknown. PLEKHA7 associates with...
9.
Goh L, Zhou X, Lee M, Lin S, Wang H, Luo Y, et al.
Dev Biol . 2013 Jul; 381(2):353-64. PMID: 23835532
Asymmetric cell division of Drosophila neural stem cells or neuroblasts is an important process which gives rise to two different daughter cells, one of which is the stem cell itself...
10.
Zhang Y, Bhunia A, Wan K, Lee M, Chan S, Yu V, et al.
J Mol Biol . 2006 Oct; 364(3):536-49. PMID: 17011577
The ratio of the levels of pro-survival and pro-apoptotic members of the Bcl-2 protein family is thought to be an important regulatory factor for determining the sensitivity of the mammalian...