Megan L Mayer
Overview
Explore the profile of Megan L Mayer including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
562
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Recent Articles
1.
Johnson A, Mayer M, Schaefer S, McNamara-Bordewick N, Hummer G, Kranzusch P
Nature
. 2024 Mar;
628(8008):657-663.
PMID: 38509367
In response to pathogen infection, gasdermin (GSDM) proteins form membrane pores that induce a host cell death process called pyroptosis. Studies of human and mouse GSDM pores have revealed the...
2.
Antine S, Johnson A, Mooney S, Leavitt A, Mayer M, Yirmiya E, et al.
Nature
. 2023 Nov;
625(7994):360-365.
PMID: 37992757
Bacteria encode hundreds of diverse defence systems that protect them from viral infection and inhibit phage propagation. Gabija is one of the most prevalent anti-phage defence systems, occurring in more...
3.
Zhang J, Tang W, Gao H, Lavine C, Shi W, Peng H, et al.
Nat Struct Mol Biol
. 2023 Jul;
30(7):980-990.
PMID: 37430064
The Omicron subvariant BA.2 has become the dominant circulating strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in many countries. Here, we have characterized structural, functional and antigenic properties...
4.
Shi W, Cai Y, Zhu H, Peng H, Voyer J, Rits-Volloch S, et al.
Nature
. 2023 Jun;
619(7969):403-409.
PMID: 37285872
The entry of SARS-CoV-2 into host cells depends on the refolding of the virus-encoded spike protein from a prefusion conformation, which is metastable after cleavage, to a lower-energy stable postfusion...
5.
Johnson A, Mayer M, Schaefer S, McNamara-Bordewick N, Hummer G, Kranzusch P
bioRxiv
. 2023 May;
PMID: 37131678
In response to pathogen infection, gasdermin (GSDM) proteins form membrane pores that induce a host cell death process called pyroptosis. Studies of human and mouse GSDM pores reveal the functions...
6.
Duncan-Lowey B, Tal N, Johnson A, Rawson S, Mayer M, Doron S, et al.
Cell
. 2023 Feb;
186(5):987-998.e15.
PMID: 36764290
RADAR is a two-protein bacterial defense system that was reported to defend against phage by "editing" messenger RNA. Here, we determine cryo-EM structures of the RADAR defense complex, revealing RdrA...
7.
Shi W, Cai Y, Zhu H, Peng H, Voyer J, Rits-Volloch S, et al.
bioRxiv
. 2022 Dec;
PMID: 36523411
Entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into host cells depends on refolding of the virus-encoded spike protein from a prefusion conformation, metastable after cleavage, to a lower...
8.
Walsh Jr R, Mayer M, Sun C, Rawson S, Nair R, Sterling S, et al.
Front Mol Biosci
. 2022 Oct;
9:960940.
PMID: 36188224
The Harvard Cryo-Electron Microscopy Center for Structural Biology, which was formed as a consortium between Harvard Medical School, Boston Children's Hospital, Dana-Farber Cancer Institute, and Massachusetts General Hospital, serves both...
9.
Zhang J, Tang W, Gao H, Lavine C, Shi W, Peng H, et al.
bioRxiv
. 2022 May;
PMID: 35547850
The Omicron subvariant BA.2 has become the dominant circulating strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in many countries. We have characterized structural, functional and antigenic properties of...
10.
Zhang J, Cai Y, Lavine C, Peng H, Zhu H, Anand K, et al.
Cell Rep
. 2022 Apr;
39(4):110729.
PMID: 35452593
The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), bearing an unusually high number of mutations, has become a dominant strain in many countries within several weeks. We...