Megan L Mayer
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Explore the profile of Megan L Mayer including associated specialties, affiliations and a list of published articles.
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17
Citations
562
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Recent Articles
11.
Johnson A, Wein T, Mayer M, Duncan-Lowey B, Yirmiya E, Oppenheimer-Shaanan Y, et al.
Science
. 2022 Jan;
375(6577):221-225.
PMID: 35025633
Gasdermin proteins form large membrane pores in human cells that release immune cytokines and induce lytic cell death. Gasdermin pore formation is triggered by caspase-mediated cleavage during inflammasome signaling and...
12.
Zhang J, Xiao T, Cai Y, Lavine C, Peng H, Zhu H, et al.
Science
. 2021 Oct;
374(6573):1353-1360.
PMID: 34698504
The Delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has outcompeted previously prevalent variants and become a dominant strain worldwide. We report the structure, function, and antigenicity of...
13.
Zhang J, Xiao T, Cai Y, Lavine C, Peng H, Zhu H, et al.
bioRxiv
. 2021 Aug;
PMID: 34426810
The Delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has outcompeted previously prevalent variants and become a dominant strain worldwide. We report here structure, function and antigenicity of...
14.
Bruhn J, Scapin G, Cheng A, Mercado B, Waterman D, Ganesh T, et al.
Front Mol Biosci
. 2021 Jul;
8:648603.
PMID: 34327213
The emerging field of microcrystal electron diffraction (MicroED) is of great interest to industrial researchers working in the drug discovery and drug development space. The promise of being able to...
15.
Kumar A, Basak S, Rao S, Gicheru Y, Mayer M, Sansom M, et al.
Nat Commun
. 2020 Jul;
11(1):3752.
PMID: 32719334
Glycinergic synapses play a central role in motor control and pain processing in the central nervous system. Glycine receptors (GlyRs) are key players in mediating fast inhibitory neurotransmission at these...
16.
Basak S, Gicheru Y, Kapoor A, Mayer M, Filizola M, Chakrapani S
Nat Commun
. 2019 Jul;
10(1):3225.
PMID: 31324772
Serotonin receptor (5-HTR) is the most common therapeutic target to manage the nausea and vomiting during cancer therapies and in the treatment of irritable bowel syndrome. Setrons, a class of...
17.
Kent G, Blackburn D, Gonzalez J, Mayer M, Wu W
Tetrahedron Lett
. 2016 Apr;
57(19):2097-2099.
PMID: 27110042
Phosphonohydrazines were prepared in good yield from corresponding arylamines by a one-pot reaction through diazotization with an organic nitrite and treatment with a trialkyl phosphite. The trialkyl phosphite is postulated...