Alpha 2.0
Login Register
» Authors » Megan K Liszewski

Megan K Liszewski

Explore the profile of Megan K Liszewski including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 513
Followers 0
Related Specialties
Microbiology
Biochemistry
Top 10 Co-Authors
Jianqing J Yu
Una ODoherty
Luis M Agosto
Clifford Baytop
Jihong Dai
Albert Bendelac
Theodore Theodosopoulos
Michael P Seiler
Laurent M Humeau
Wei Yang
Published In
Virology
J Virol
PLoS Pathog
Methods
Nat Immunol
Affiliations
Soon will be listed here.
Recent Articles
1.
Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling
Seiler M, Mathew R, Liszewski M, Spooner C, Spooner C, Barr K, et al.
Nat Immunol . 2012 Feb; 13(3):264-71. PMID: 22306690
Interactions driven by the T cell antigen receptor (TCR) determine the lineage fate of CD4(+)CD8(+) thymocytes, but the molecular mechanisms that induce the lineage-determining transcription factors are unknown. Here we...
2.
Elite suppressors harbor low levels of integrated HIV DNA and high levels of 2-LTR circular HIV DNA compared to HIV+ patients on and off HAART
Graf E, Mexas A, Yu J, Shaheen F, Liszewski M, Di Mascio M, et al.
PLoS Pathog . 2011 Mar; 7(2):e1001300. PMID: 21383972
Elite suppressors (ES) are a rare population of HIV-infected individuals that are capable of naturally controlling the infection without the use of highly active anti-retroviral therapy (HAART). Patients on HAART...
3.
Patients on HAART often have an excess of unintegrated HIV DNA: implications for monitoring reservoirs
Agosto L, Liszewski M, Mexas A, Graf E, Pace M, Yu J, et al.
Virology . 2010 Oct; 409(1):46-53. PMID: 20970154
HIV establishes a latent reservoir early in infection that is resistant to anti-retroviral therapy and has a slow rate of decay. It is thought that the majority of HIV DNA...
4.
The CXCR4-tropic human immunodeficiency virus envelope promotes more-efficient gene delivery to resting CD4+ T cells than the vesicular stomatitis virus glycoprotein G envelope
Agosto L, Yu J, Liszewski M, Baytop C, Korokhov N, Humeau L, et al.
J Virol . 2009 Jun; 83(16):8153-62. PMID: 19493998
Current gene transfer protocols for resting CD4(+) T cells include an activation step to enhance transduction efficiency. This step is performed because it is thought that resting cells are resistant...
5.
Human immunodeficiency virus integrates directly into naive resting CD4+ T cells but enters naive cells less efficiently than memory cells
Dai J, Agosto L, Baytop C, Yu J, Pace M, Liszewski M, et al.
J Virol . 2009 Feb; 83(9):4528-37. PMID: 19211752
Resting CD4(+) T cells restrict human immunodeficiency virus (HIV) infection at or before reverse transcription, resulting in slower kinetics of reverse transcription. In a previous study, we showed that, despite...
6.
Detecting HIV-1 integration by repetitive-sampling Alu-gag PCR
Liszewski M, Yu J, ODoherty U
Methods . 2009 Feb; 47(4):254-60. PMID: 19195495
In this review, we compare four assays that are currently used to measure HIV integration and discuss their strengths and weaknesses. We then outline advances that have been made toward...
7.
A more precise HIV integration assay designed to detect small differences finds lower levels of integrated DNA in HAART treated patients
Yu J, Wu T, Liszewski M, Dai J, Swiggard W, Baytop C, et al.
Virology . 2008 Jul; 379(1):78-86. PMID: 18649912
Many studies report the level of total viral DNA in HIV-infected patients, but few studies report the level of integrated DNA. It is important to measure integrated DNA in HIV-infected...