Meera V Sundaram
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Explore the profile of Meera V Sundaram including associated specialties, affiliations and a list of published articles.
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51
Citations
1294
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Recent Articles
1.
Schmidt H, Darwin C, Sundaram M
Dev Biol
. 2024 Nov;
517:265-277.
PMID: 39489317
The surface of epithelial tissues is covered by an apical extracellular matrix (aECM). The aECMs of different tissues have distinct compositions to serve distinct functions, yet how a particular cell...
2.
Serra N, Sundaram M
MicroPubl Biol
. 2024 Oct;
2024.
PMID: 39391293
nematodes possess expanded families of Hedgehog related (Hh-r) and Patched/Dispatched-related (PTR) proteins but their functional relationship remains unclear. Here we investigated whether CHE-14 , the closest ortholog for the Hedgehog...
3.
Schmidt H, Darwin C, Sundaram M
bioRxiv
. 2024 Sep;
PMID: 39282387
The surface of epithelial tissues is covered by an apical extracellular matrix (aECM). The aECMs of different tissues have distinct compositions to serve distinct functions, yet how a particular cell...
4.
Ponomarova O, Starbard A, Belfi A, Anderson A, Sundaram M, Walhout A
Life Sci Alliance
. 2024 Jul;
7(10).
PMID: 39009411
In humans, a neomorphic isocitrate dehydrogenase mutation () causes increased levels of cellular D-2-hydroxyglutarate (D-2HG), a proposed oncometabolite. However, the physiological effects of increased D-2HG and whether additional metabolic changes...
5.
Sundaram M, Pujol N
Genetics
. 2024 Jul;
227(4.
PMID: 38995735
Apical extracellular matrices (aECMs) coat the exposed surfaces of animal bodies to shape tissues, influence social interactions, and protect against pathogens and other environmental challenges. In the nematode Caenorhabditis elegans,...
6.
Serra N, Darwin C, Sundaram M
Genetics
. 2024 May;
227(4).
PMID: 38739761
In Caenorhabditis elegans, expanded families of divergent Hedgehog-related and patched-related proteins promote numerous processes ranging from epithelial and sense organ development to pathogen responses to cuticle shedding during the molt...
7.
Ponomarova O, Starbard A, Belfi A, Anderson A, Sundaram M, Walhout A
bioRxiv
. 2024 Apr;
PMID: 38559246
The isocitrate dehydrogenase neomorphic mutation ( ) generates increased levels of cellular D-2-hydroxyglutarate (D-2HG), a proposed oncometabolite. However, the physiological effects of increased D-2HG and whether additional metabolic changes occur...
8.
Serra N, Darwin C, Sundaram M
bioRxiv
. 2024 Jan;
PMID: 38234847
In , divergent Hedgehog-related (Hh-r) and Patched-related (PTR) proteins promote numerous processes ranging from epithelial and sense organ development to pathogen responses to cuticle shedding during the molt cycle. Here...
9.
Birnbaum S, Cohen J, Belfi A, Murray J, Adams J, Chisholm A, et al.
PLoS Genet
. 2023 Sep;
19(9):e1010944.
PMID: 37721936
Some types of collagens, including transmembrane MACIT collagens and C. elegans cuticle collagens, are N-terminally cleaved at a dibasic site that resembles the consensus for furin or other proprotein convertases...
10.
Barker T, Chan F, Carvalho A, Sundaram M
MicroPubl Biol
. 2023 Jul;
2023.
PMID: 37396793
The vulva is a polarized epithelial tube that has been studied extensively as a model for cell-cell signaling, cell fate specification, and tubulogenesis. Here we used endogenous fusions to show...