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Md Nasimuzzaman

Explore the profile of Md Nasimuzzaman including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 239
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Recent Articles
1.
Smith R, Bloomer H, Fink D, Keyvanfar K, Nasimuzzaman M, Sancheznieto F, et al.
Hum Gene Ther . 2022 Sep; 33(23-24):1293-1304. PMID: 36094106
gene therapy procedures targeting hematopoietic stem and progenitor cells (HSPCs) predominantly utilize lentivirus-based vectors for gene transfer. We provide the first pre-clinical evidence of the therapeutic utility of a foamy...
2.
Narciso M, Hoeting B, James J, VandenHeuvel K, Nasimuzzaman M
EJHaem . 2022 Jul; 2(3):462-465. PMID: 35844706
Sickle cell anemia (SCA) causes nephropathy which may progress to kidney failure. To determine if soluble fibrinogen (Fib) can prevent kidney damage in mice with SCA, we performed bone marrow...
3.
Nasimuzzaman M, Villaveces S, van der Loo J, Alla S
J Vis Exp . 2022 Jan; (179). PMID: 35098946
Adeno-associated viruses (AAV) are promising vectors for gene therapy applications. Here, the AAV2 vector is produced by co-culture of Spodoptera frugiperda (Sf9) cells with Sf9 cells infected with baculovirus (BV)-AAV2-GFP...
4.
Nasimuzzaman M, Waris G, Mikolon D, Stupack D, Siddiqui A
J Virol . 2020 Sep; 94(19). PMID: 32934071
No abstract available.
5.
Nasimuzzaman M, Malik P
Blood Adv . 2019 Oct; 3(20):3170-3180. PMID: 31648337
Sickle cell disease (SCD) is an inherited monogenic red blood cell disorder affecting millions worldwide. SCD causes vascular occlusions, chronic hemolytic anemia, and cumulative organ damage such as nephropathy, pulmonary...
6.
Narciso M, Nasimuzzaman M
J Vis Exp . 2019 May; (147). PMID: 31132069
Platelets are purified from whole blood to study their functional properties, which should be free from red blood cells (RBC), white blood cells (WBC), and plasma proteins. We describe here...
7.
Nasimuzzaman M, Arumugam P, Mullins E, James J, VandenHeuvel K, Narciso M, et al.
Blood Adv . 2019 May; 3(9):1519-1532. PMID: 31076408
Sickle cell anemia (SCA) is caused by a point mutation in the β-globin gene that leads to devastating downstream consequences including chronic hemolytic anemia, episodic vascular occlusion, and cumulative organ...
8.
Nasimuzzaman M, van der Loo J, Malik P
J Vis Exp . 2018 Apr; (134). PMID: 29683451
Baculovirus has traditionally been used for the production of recombinant protein and vaccine. However, more recently, baculovirus is emerging as a promising vector for gene therapy application. Here, baculovirus is...
9.
Nasimuzzaman M, Lynn D, van der Loo J, Malik P
Mol Ther Methods Clin Dev . 2016 Dec; 3:16071. PMID: 27933303
Baculoviruses are commonly used for recombinant protein and vaccine production. Baculoviruses are nonpathogenic to vertebrates, have a large packaging capacity, display broad host and cell type tropism, infect both dividing...
10.
Nasimuzzaman M, Lynn D, Ernst R, Beuerlein M, Smith R, Shrestha A, et al.
Mol Ther Methods Clin Dev . 2016 Oct; 3:16004. PMID: 27722179
Compared to other integrating viral vectors, foamy virus (FV) vectors have distinct advantages as a gene transfer tool, including their nonpathogenicity, the ability to carry larger transgene cassettes, and increased...