Md Maksudul Alam
Overview
Explore the profile of Md Maksudul Alam including associated specialties, affiliations and a list of published articles.
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12
Citations
323
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Recent Articles
1.
Alam M, Fermin J, Knackstedt M, Noonan M, Powell T, Goodreau L, et al.
Oncotarget
. 2023 Feb;
14:85-95.
PMID: 36745547
mutant head and neck squamous cell carcinoma (HNSCC) patients exhibit poor clinical outcomes with 50-60% recurrence rates in advanced stage patients. In a recent phase II clinical trial, adjuvant therapy...
2.
Li H, Liu Z, Liu L, Zhang H, Han C, Girard L, et al.
Cell Rep Med
. 2022 May;
3(3):100554.
PMID: 35492873
Mutations in in non-small cell lung cancer (NSCLC) are associated with poor patient responses to immune checkpoint blockade (ICB), and introduction of a () mutation into murine lung adenocarcinomas driven...
3.
Alam M, Fermin J, Spiller P, Burnett C, Rong X, Moore-Medlin T, et al.
Mol Carcinog
. 2021 Oct;
61(1):33-44.
PMID: 34598317
TP53 is the most frequently mutated gene in head and neck squamous cell carcinoma (HNSCC). Patients with HPV-negative TP53 mutant HNSCC have the worst prognosis, necessitating additional agents for treatment....
4.
Khandelwal A, Kent B, Hillary S, Alam M, Ma X, Gu X, et al.
Mol Carcinog
. 2019 Jun;
58(10):1715-1725.
PMID: 31254372
Cutaneous squamous cell carcinoma (cSCC) is a keratinocyte-derived invasive and metastatic tumor of the skin. It is the second-most commonly diagnosed form of skin cancer striking 200 000 Americans annually....
5.
Li H, Cuevas I, Zhang M, Lu C, Alam M, Fu Y, et al.
J Clin Invest
. 2018 Aug;
128(9):4179-4191.
PMID: 30124468
Mutations underlie all cancers, and their identification and study are the foundation of cancer biology. We describe what we believe to be a novel approach to mutagenesis and cancer studies...
6.
Alam M, Lal S, Fitzgerald K, Zhang L
Clin Transl Med
. 2018 Mar;
7(1):8.
PMID: 29497871
In this Correction, the authors would like to acknowledge that the original publication of the article "A holistic view of cancer bioenergetics: mitochondrial function and respiration play fundamental roles in...
7.
Akbay E, Koyama S, Liu Y, Dries R, Bufe L, Silkes M, et al.
J Thorac Oncol
. 2017 May;
12(8):1268-1279.
PMID: 28483607
Introduction: Proinflammatory cytokine interleukin-17A (IL-17A) is overexpressed in a subset of patients with lung cancer. We hypothesized that IL-17A promotes a protumorigenic inflammatory phenotype and inhibits antitumor immune responses. Methods:...
8.
Lal S, Alam M, Hooda J, Shah A, Cao T, Xuan Z, et al.
Biosci Rep
. 2016 May;
36(3).
PMID: 27190130
Recent experimental evidence increasingly shows that the dysregulation of cellular bioenergetics is associated with a wide array of common human diseases, including cancer, neurological diseases and diabetes. Respiration provides a...
9.
Alam M, Sohoni S, Kalainayakan S, Garrossian M, Zhang L
BMC Cancer
. 2016 Feb;
16:150.
PMID: 26911235
Background: Aberrant Hedgehog (Hh) signaling is associated with the development of many cancers including prostate cancer, gastrointestinal cancer, lung cancer, pancreatic cancer, ovarian cancer, and basal cell carcinoma. The Hh...
10.
Alam M, Lal S, Fitzgerald K, Zhang L
Clin Transl Med
. 2016 Jan;
5(1):3.
PMID: 26812134
Since Otto Warburg made the first observation that tumor cells exhibit altered metabolism and bioenergetics in the 1920s, many scientists have tried to further the understanding of tumor bioenergetics. Particularly,...