May Poh Lai
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Explore the profile of May Poh Lai including associated specialties, affiliations and a list of published articles.
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5
Citations
18
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Recent Articles
1.
Lin H, Riching K, Lai M, Lu D, Cheng R, Qi X, et al.
ACS Med Chem Lett
. 2024 Aug;
15(8):1367-1375.
PMID: 39140070
Target protein degradation (TPD) has emerged as a revolutionary approach in drug discovery, leveraging the cell's intrinsic machinery to selectively degrade disease-associated proteins. Nanoluciferase (nLuc) fusion proteins and the NanoBiT...
2.
Lin H, Riching K, Lai M, Lu D, Cheng R, Qi X, et al.
bioRxiv
. 2024 May;
PMID: 38798562
Target protein degradation (TPD) has emerged as a revolutionary approach in drug discovery, leveraging the cell's intrinsic machinery to selectively degrade disease-associated proteins. Proteolysis-Targeting Chimeras (PROTACs) exemplify this strategy, exploiting...
3.
Kartal O, Andres F, Lai M, Nehme R, Cottier K
SLAS Discov
. 2021 May;
26(8):995-1003.
PMID: 34049465
Surface-based biophysical methods for measuring binding kinetics of molecular interactions, such as surface plasmon resonance (SPR) or grating-coupled interferometry (GCI), are now well established and widely used in drug discovery....
4.
Lai M, Katz F, Bernard C, Storch J, Stark R
Protein Sci
. 2020 Apr;
29(7):1606-1617.
PMID: 32298508
Two different members of the fatty acid-binding protein (FABP) family are found in enterocyte cells of the gastrointestinal system, namely liver-type and intestinal fatty acid-binding proteins (LFABP and IFABP, also...
5.
Wang Q, Rizk S, Bernard C, Lai M, Kam D, Storch J, et al.
Biochem Biophys Rep
. 2017 Sep;
10:318-324.
PMID: 28955759
Adipocyte fatty acid-binding protein (AFABP: FABP4) is a member of the intracellular lipid-binding protein family that is thought to target long-chain fatty acids to nuclear receptors such as peroxisome proliferator-activated...