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Maxmore Chaibva

Explore the profile of Maxmore Chaibva including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 163
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Recent Articles
1.
Arndt J, Chaibva M, Beasley M, Kiani Karanji A, Ghassabi Kondalaji S, Khakinejad M, et al.
Biochemistry . 2019 Dec; 59(4):436-449. PMID: 31814404
Huntington's disease is a genetic neurodegenerative disorder characterized by the formation of amyloid fibrils of the huntingtin protein (htt). The 17-residue N-terminal region of htt (Nt) has been implicated in...
2.
Chaibva M, Gao X, Jain P, Campbell 4th W, Frey S, Legleiter J
ACS Omega . 2018 Feb; 3(1):273-285. PMID: 29399649
Huntington disease (HD) is an inherited neurodegenerative disease caused by the expansion beyond a critical threshold of a polyglutamine (polyQ) tract near the N-terminus of the huntingtin (htt) protein. Expanded...
3.
Chaibva M, Jawahery S, Pilkington 4th A, Arndt J, Sarver O, Valentine S, et al.
Biophys J . 2016 Jul; 111(2):349-362. PMID: 27463137
Huntington's disease (HD) is a genetic neurodegenerative disorder caused by an expanded polyglutamine (polyQ) domain near the N-terminus of the huntingtin (htt) protein. Expanded polyQ leads to htt aggregation. The...
4.
Gao X, Campbell 4th W, Chaibva M, Jain P, Leslie A, Frey S, et al.
Biochemistry . 2015 Dec; 55(1):92-102. PMID: 26652744
Huntington's disease (HD) is an inherited neurodegenerative disease caused by abnormally long CAG-repeats in the huntingtin gene that encode an expanded polyglutamine (polyQ) domain near the N-terminus of the huntingtin...
5.
Arndt J, Chaibva M, Legleiter J
Biomol Concepts . 2015 Mar; 6(1):33-46. PMID: 25741791
Huntington's disease (HD) is caused by a polyglutamine (polyQ) domain that is expanded beyond a critical threshold near the N-terminus of the huntingtin (htt) protein, directly leading to htt aggregation....
6.
Chaibva M, Burke K, Legleiter J
Biochemistry . 2014 Mar; 53(14):2355-65. PMID: 24670006
Huntington disease (HD) is a genetic neurodegenerative disease caused by an expanded polyglutamine (polyQ) domain in the first exon of the huntingtin (Htt) protein, facilitating its aggregation. Htt interacts with...
7.
Burke K, Hensal K, Umbaugh C, Chaibva M, Legleiter J
Biochim Biophys Acta . 2013 May; 1828(8):1953-61. PMID: 23643759
Huntington's Disease (HD) is a neurodegenerative disorder that is defined by the accumulation of nanoscale aggregates comprised of the huntingtin (htt) protein. Aggregation is directly caused by an expanded polyglutamine...