Mauro Corrado
Overview
Explore the profile of Mauro Corrado including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
1997
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Recent Articles
1.
Garcia B, Melchinger P, Medeiros T, Hendrix S, Prabhu K, Corrado M, et al.
EMBO J
. 2024 Oct;
43(23):5837-5856.
PMID: 39433901
The mevalonate pathway produces essential lipid metabolites such as cholesterol. Although this pathway is negatively regulated by metabolic intermediates, little is known of the metabolites that positively regulate its activity....
2.
Cosgrove J, Marcais A, Hartmann F, Bergthaler A, Zanoni I, Corrado M, et al.
Nat Metab
. 2024 Apr;
6(5):779-782.
PMID: 38605184
No abstract available.
3.
Villa M, Sanin D, Apostolova P, Corrado M, Kabat A, Cristinzio C, et al.
Nat Commun
. 2024 Jan;
15(1):451.
PMID: 38200005
Immune cells must adapt to different environments during the course of an immune response. Here we study the adaptation of CD8 T cells to the intestinal microenvironment and how this...
4.
Guhathakurta S, Erdogdu N, Hoffmann J, Grzadzielewska I, Schendzielorz A, Seyfferth J, et al.
Nat Metab
. 2023 Oct;
5(11):1931-1952.
PMID: 37813994
Reversible acetylation of mitochondrial proteins is a regulatory mechanism central to adaptive metabolic responses. Yet, how such functionally relevant protein acetylation is achieved remains unexplored. Here we reveal an unprecedented...
5.
Corrado M, Frezza C
Cell Chem Biol
. 2023 Sep;
30(9):1012-1014.
PMID: 37738953
Metabolic competition within the tumor microenvironment (TME) shapes the efficacy of anticancer immunity. In the August 3 issue of Nature, Guo et al. show that glutamine is an intercellular metabolic...
6.
Vaikunthanathan T, Landmann E, Correa D, Romano M, Trevelin S, Peng Q, et al.
EBioMedicine
. 2023 Sep;
95:104778.
PMID: 37657135
Background: Dysregulated inflammatory responses and oxidative stress are key pathogenic drivers of chronic inflammatory diseases such as liver cirrhosis (LC). Regulatory T cells (Tregs) are essential to prevent excessive immune...
7.
Humblin E, Korpas I, Lu J, Filipescu D, van der Heide V, Goldstein S, et al.
Sci Immunol
. 2023 Aug;
8(86):eadg0878.
PMID: 37624910
During persistent antigen stimulation, such as in chronic infections and cancer, CD8 T cells differentiate into a hypofunctional programmed death protein 1-positive (PD-1) exhausted state. Exhausted CD8 T cell responses...
8.
Villa M, Sanin D, Apostolova P, Corrado M, Kabat A, Cristinzio C, et al.
bioRxiv
. 2023 Mar;
PMID: 36993703
Immune cells must adapt to different environments during the course of an immune response. We studied the adaptation of CD8 T cells to the intestinal microenvironment and how this process...
9.
Edwards-Hicks J, Apostolova P, Buescher J, Maib H, Stanczak M, Corrado M, et al.
Nat Immunol
. 2023 Feb;
24(3):516-530.
PMID: 36732424
How lipidome changes support CD8 effector T (T) cell differentiation is not well understood. Here we show that, although naive T cells are rich in polyunsaturated phosphoinositides (PIP with 3-4...
10.
Baixauli F, Piletic K, Puleston D, Villa M, Field C, Flachsmann L, et al.
Nature
. 2022 Sep;
610(7932):555-561.
PMID: 36171294
CD4 T cell differentiation requires metabolic reprogramming to fulfil the bioenergetic demands of proliferation and effector function, and enforce specific transcriptional programmes. Mitochondrial membrane dynamics sustains mitochondrial processes, including respiration...