Mauri Reunanen
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Explore the profile of Mauri Reunanen including associated specialties, affiliations and a list of published articles.
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11
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2072
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Recent Articles
1.
Krokki O, Bloigu R, Ansakorpi H, Reunanen M, Remes A
Mult Scler Relat Disord
. 2015 Apr;
3(1):72-7.
PMID: 25877976
Objective: There is increasing interest in the survival of multiple sclerosis (MS). MS itself may decrease life expectancy; however, several other comorbid diseases may also influence survival. We aimed to...
2.
Beecham A, Patsopoulos N, Xifara D, Davis M, Kemppinen A, Cotsapas C, et al.
Nat Genet
. 2013 Oct;
45(11):1353-60.
PMID: 24076602
Using the ImmunoChip custom genotyping array, we analyzed 14,498 subjects with multiple sclerosis and 24,091 healthy controls for 161,311 autosomal variants and identified 135 potentially associated regions (P < 1.0...
3.
Sawcer S, Hellenthal G, Pirinen M, Spencer C, Patsopoulos N, Moutsianas L, et al.
Nature
. 2011 Aug;
476(7359):214-9.
PMID: 21833088
Multiple sclerosis is a common disease of the central nervous system in which the interplay between inflammatory and neurodegenerative processes typically results in intermittent neurological disturbance followed by progressive accumulation...
4.
Jakkula E, Leppa V, Sulonen A, Varilo T, Kallio S, Kemppinen A, et al.
Am J Hum Genet
. 2010 Feb;
86(2):285-91.
PMID: 20159113
Genetic risk for multiple sclerosis (MS) is thought to involve both common and rare risk alleles. Recent GWAS and subsequent meta-analysis have established the critical role of the HLA locus...
5.
Kallio S, Jakkula E, Purcell S, Suvela M, Koivisto K, Tienari P, et al.
Hum Mol Genet
. 2009 Feb;
18(9):1670-83.
PMID: 19221116
Large case-control genome-wide association studies primarily expose common variants contributing to disease pathogenesis with modest effects. Thus, alternative strategies are needed to tackle rare, possibly more penetrant alleles. One strategy...
6.
Bonetti A, Koivisto K, Pirttila T, Elovaara I, Reunanen M, Laaksonen M, et al.
J Neuroimmunol
. 2009 Feb;
208(1-2):119-24.
PMID: 19195718
A possible role of allelic variation on chromosome 19q13 in multiple sclerosis (MS) susceptibility has been suggested. We tested association of sixteen 19q13 markers with MS in 459 families. Nominally...
7.
Kemppinen A, Suvela M, Tienari P, Elovaara I, Koivisto K, Pirttila T, et al.
Eur J Hum Genet
. 2009 Jan;
17(6):840-3.
PMID: 19142207
Single-nucleotide polymorphisms (SNPs) in the 3' region of myosin IXB (MYO9B) gene have recently been reported to associate with different inflammatory or autoimmune diseases. We monitored for the association of...
8.
Sulonen A, Kallio S, Ellonen P, Suvela M, Elovaara I, Koivisto K, et al.
J Neuroimmunol
. 2008 Nov;
206(1-2):86-90.
PMID: 19019460
Loss-of-function mutations of DAP12 and TREM2 cause a recessively inherited disease PLOSL, manifesting in brain white matter. The genes of the DAP12-TREM2 signaling receptor are located on 19q13.12 and 6p21.1,...
9.
Ruutiainen J, Elovaara I, Pirttila T, Eralinna J, Farkkila M, Koivisto K, et al.
Duodecim
. 2006 Nov;
122(18):2181-2.
PMID: 17115639
No abstract available.
10.
Riise Stensland H, Saarela J, Bronnikov D, Parkkonen M, Jokiaho A, Palotie A, et al.
J Neuroimmunol
. 2005 Sep;
170(1-2):122-33.
PMID: 16169605
Linkage analyses have identified four major MS susceptibility loci in Finns. Here we have fine mapped the region on chromosome 5p in 28 Finnish MS families. Marker D5S416 provided the...