Matthijs Moerland
Overview
Explore the profile of Matthijs Moerland including associated specialties, affiliations and a list of published articles.
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89
Citations
727
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Recent Articles
1.
Hogenelst K, Krone T, Eveleens Maarse B, Warnke I, Snabel J, van den Broek T, et al.
Brain Behav Immun Health
. 2024 Dec;
43:100918.
PMID: 39717875
Prebiotic dietary fiber (PDF) may reduce feelings of stress or improve mood in healthy individuals. Yet gut intervention studies that focus on mood in daily life are lacking and few...
2.
van Ruissen M, van Kraaij S, Gal P, Bakker W, Hijma H, Groeneveld G, et al.
J Exp Pharmacol
. 2024 Sep;
16:285-294.
PMID: 39308849
Dermal allyl isothiocyanate (AITC) administration and whole-body heat stress (WBHS) are two challenge models that are used to evaluate physiological mechanisms of vasodilation and pharmacological activity in humans. Their exact...
3.
van Kraaij S, Eveleens Maarse B, Hoevenaars F, Warnke I, de Kam M, Moerland M, et al.
Clin Physiol Funct Imaging
. 2024 Sep;
45(1):e12904.
PMID: 39308427
Purpose: Endothelial dysfunction is a pathophysiological change preceding many cardiovascular events. Measuring improvements of endothelial function is challenging when function is already optimal, which may be remediated using a physiological...
4.
Extending the IMQ Model: Deep Characterization of the Human TLR7 Response for Early Drug Development
van den Noort J, Assil S, Ronner M, Osse M, Pot I, Yavuz Y, et al.
Inflammation
. 2024 Aug;
PMID: 39183259
Imiquimod (IMQ; brand name Aldara®) is a registered topical agent that has been proven to induce local inflammation via the Toll-like receptor (TLR)7 pathway. The purpose of this study was...
5.
In t Veld A, Eveleens Maarse B, Juachon M, Meziyerh S, de Vries A, van Rijn A, et al.
Clin Transl Sci
. 2024 Jun;
17(6):e13860.
PMID: 38923308
The recommended immunosuppressive treatment after kidney transplantation consists of tacrolimus, mycophenolate mofetil, and low-dose corticosteroids. Drug concentrations are monitored using therapeutic drug monitoring (TDM), which does not necessarily correlate with...
6.
Eveleens Maarse B, Ronner M, Jansen M, Niemeyer-van der Kolk T, In t Veld A, Klaassen E, et al.
Immunol Res
. 2024 May;
72(4):776-787.
PMID: 38748319
The gut microbiome can modulate systemic inflammation and is therefore target for immunomodulation. Immunomodulating effects of EDP1815, a bacterial commensal strain of Prevotella histicola, were studied in healthy participants. Effects...
7.
Jodl S, Ten Voorde W, Klein S, Wagenfeld A, Zollmann F, Feldmuller M, et al.
Clin Transl Sci
. 2024 Mar;
17(3):e13771.
PMID: 38511583
This study evaluated and characterized the pharmacological activity of the orally administered interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitors BAY1834845 (zabedosertib) and BAY1830839 in healthy male volunteers. Participants received one of...
8.
Eveleens Maarse B, Eggink H, Warnke I, Bijlsma S, van den Broek T, Oosterman J, et al.
Nutr Metab Cardiovasc Dis
. 2024 Mar;
34(6):1416-1426.
PMID: 38499450
Background And Aims: The gut microbiome exerts important roles in health, e.g., functions in metabolism and immunology. These functions are often exerted via short-chain fatty acid (SCFA) production by gut...
9.
Yfanti C, Vestbjerg B, Vant Westende J, Edvardsson N, Meseguer Monfort L, Olesen M, et al.
Br J Clin Pharmacol
. 2023 Nov;
90(4):1027-1035.
PMID: 37990600
Aims: AP30663 is a novel compound under development for pharmacological conversion of atrial fibrillation by targeting the small conductance Ca activated K (K2) channel. The aim of this extension phase...
10.
Assil S, Buters T, Hameeteman P, Hallard C, Treijtel N, Niemeyer-van der Kolk T, et al.
Front Immunol
. 2023 Aug;
14:1197650.
PMID: 37545524
Imiquimod (IMQ) is a topical agent that induces local inflammation the Toll-like receptor 7 pathway. Recently, an IMQ-driven skin inflammation model was developed in healthy volunteers for proof-of-pharmacology trials. The...