Matthijs Luxen
Overview
Explore the profile of Matthijs Luxen including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
25
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0
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Recent Articles
1.
Wang Z, Dayang E, Zwiers P, Hernandez Garcia M, Luxen M, van Meurs M, et al.
Biomedicines
. 2024 Aug;
12(8).
PMID: 39200137
Background: Sepsis is an uncontrolled systemic inflammatory response to an infection that can result in acute failure of the function of the lung called acute respiratory distress syndrome. Leukocyte recruitment...
2.
Wang Z, Dayang E, Zwiers P, Hernandez Garcia M, Luxen M, van Meurs M, et al.
J Leukoc Biol
. 2024 Jul;
116(6):1479-1497.
PMID: 38953175
Sepsis is a dysregulated systemic inflammatory response to an infection, which can lead to multiple organ dysfunction syndrome that includes the kidney. Leukocyte recruitment is an important process of the...
3.
Luxen M, Zwiers P, Jongman R, Moser J, Pultar M, Skalicky S, et al.
Thromb Res
. 2024 Apr;
237:112-128.
PMID: 38579513
Background: Acute kidney injury (AKI) in sepsis patients increases patient mortality. Endothelial cells are important players in the pathophysiology of sepsis-associated AKI (SA-AKI), yet knowledge regarding their spatiotemporal involvement in...
4.
Luxen M, Zwiers P, Meester F, Jongman R, Kuiper T, Moser J, et al.
Am J Physiol Renal Physiol
. 2023 Jul;
325(3):F299-F316.
PMID: 37410897
Endothelial cells in blood vessels in the kidney exert different functions depending on the (micro)vascular bed they are located in. The present study aimed to investigate microRNA and mRNA transcription...
5.
Ellermann S, Jongman R, Luxen M, Kuiper T, Plantinga J, Moser J, et al.
Front Pharmacol
. 2022 Dec;
13:992262.
PMID: 36532777
Major surgery induces systemic inflammation leading to pro-inflammatory activation of endothelial cells. Endothelial inflammation is one of the drivers of postoperative organ damage, including acute kidney injury Tumour Necrosis Factor...
6.
Luxen M, van Meurs M, Molema G
Front Immunol
. 2022 May;
13:867625.
PMID: 35634305
Sepsis is a devastating clinical condition that can lead to multiple organ failure and death. Despite advancements in our understanding of molecular mechanisms underlying sepsis and sepsis-associated multiple organ failure,...
7.
Dayang E, Luxen M, Kuiper T, Yan R, Rangarajan S, van Meurs M, et al.
Biomed Pharmacother
. 2020 Dec;
133:111073.
PMID: 33378972
Sepsis is a life-threatening condition often leading to multiple organ failure for which currently no pharmacological treatment is available. Endothelial cells (EC) are among the first cells to respond to...