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Matthieu Rousseau

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Articles 17
Citations 908
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Recent Articles
1.
Rousseau M, Lacerda Mariano L, Canton T, Ingersoll M
Sci Immunol . 2023 May; 8(83):eabn4332. PMID: 37235683
Urinary tract infection (UTI) is one of the most prevalent human bacterial infections. New therapeutic approaches, including vaccination and immunotherapy, are urgently needed to combat the rapid global dissemination of...
2.
Lacerda Mariano L, Rousseau M, Varet H, Legendre R, Gentek R, Saenz Coronilla J, et al.
Sci Adv . 2020 Nov; 6(48). PMID: 33239294
Resident macrophages are abundant in the bladder, playing key roles in immunity to uropathogens. Yet, whether they are heterogeneous, where they come from, and how they respond to infection remain...
3.
Lupo F, Rousseau M, Canton T, Ingersoll M
J Immunol . 2020 Oct; 205(10):2763-2777. PMID: 33055280
Bacterial prostatitis affects 1% of men, with increased incidence in the elderly. Acute bacterial prostatitis frequently progresses to chronicity, marked by recurrent episodes interspersed with asymptomatic periods of variable duration....
4.
Zychlinsky Scharff A, Rousseau M, Lacerda Mariano L, Canton T, Consiglio C, Albert M, et al.
JCI Insight . 2019 May; 5. PMID: 31145099
Sex-based differences influence incidence and outcome of infectious disease. Women have a significantly greater incidence of urinary tract infection (UTI) than men, yet, conversely, male UTI is more persistent with...
5.
Duchez A, Boudreau L, Naika G, Rousseau M, Cloutier N, Levesque T, et al.
Prostaglandins Other Lipid Mediat . 2019 May; 143:106340. PMID: 31129176
Phospholipase As (PLA) play a key role in generation of eicosanoids. Cytosolic PLAα (cPLAα) is constitutively expressed in most cells, whereas IIA secreted PLA (sPLA-IIA) is induced during inflammation and...
6.
Rousseau M, Goh H, Holec S, Albert M, Williams R, Ingersoll M, et al.
JCI Insight . 2016 Oct; 1(15):e88178. PMID: 27699248
Catheter-associated urinary tract infections (CAUTI) are the most common hospital-associated infections. Here, we report that bladder catheterization initiated a persistent sterile inflammatory reaction within minutes of catheter implantation. Catheterization resulted...
7.
Marcoux G, Duchez A, Rousseau M, Levesque T, Boudreau L, Thibault L, et al.
Platelets . 2016 Sep; 28(3):272-280. PMID: 27681879
On activation, platelets release vesicles called microparticles (MPs). MPs are heterogeneous with regard to the presence or absence of mitochondria. We quantified MPs in platelet concentrates (PCs) taking their mitochondrial...
8.
Dieude M, Bell C, Turgeon J, Beillevaire D, Pomerleau L, Yang B, et al.
Sci Transl Med . 2015 Dec; 7(318):318ra200. PMID: 26676607
Autoantibodies to components of apoptotic cells, such as anti-perlecan antibodies, contribute to rejection in organ transplant recipients. However, mechanisms of immunization to apoptotic components remain largely uncharacterized. We used large-scale...
9.
Laffont B, Corduan A, Rousseau M, Duchez A, Lee C, Boilard E, et al.
Thromb Haemost . 2015 Sep; 115(2):311-23. PMID: 26333874
Platelet microparticles (MPs) represent the most abundant MPs subtype in the circulation, and can mediate intercellular communication through delivery of bioactives molecules, such as cytokines, proteins, lipids and RNAs. Here,...
10.
Duchez A, Boudreau L, Naika G, Bollinger J, Belleannee C, Cloutier N, et al.
Proc Natl Acad Sci U S A . 2015 Jun; 112(27):E3564-73. PMID: 26106157
Platelets are anucleated blood elements highly potent at generating extracellular vesicles (EVs) called microparticles (MPs). Whereas EVs are accepted as an important means of intercellular communication, the mechanisms underlying platelet...