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Matthieu Jules

Explore the profile of Matthieu Jules including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 1539
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Recent Articles
1.
Tanneur I, Dervyn E, Guerin C, Kon Kam King G, Jules M, Nicolas P
Nucleic Acids Res . 2025 Mar; 53(5). PMID: 40057377
Polymerase errors during DNA replication are a major source of point mutations in genomes. The spontaneous mutation rate also depends on the counteracting activity of DNA repair mechanisms, with mutator...
2.
Bidnenko V, Chastanet A, Pechoux C, Redko-Hamel Y, Pellegrini O, Durand S, et al.
J Biol Chem . 2024 Oct; 300(12):107905. PMID: 39427753
Termination factor Rho, responsible for the main factor-dependent pathway of transcription termination and the major inhibitor of antisense transcription, is an emerging regulator of various physiological processes in microorganisms. In...
3.
Guesdon G, Gourgues G, Rideau F, Ipoutcha T, Manso-Silvan L, Jules M, et al.
ACS Synth Biol . 2023 Oct; 12(11):3252-3266. PMID: 37843014
The genetic engineering of genome fragments larger than 100 kbp is challenging and requires both specific methods and cloning hosts. The yeast is considered as a host of choice for...
4.
Wagner L, Jules M, Borkowski O
Comput Struct Biotechnol J . 2023 Jun; 21:3173-3182. PMID: 37333859
Because they mimic cells while offering an accessible and controllable environment, lysate-based cell-free systems (CFS) have emerged as valuable biotechnology tools for synthetic biology. Historically used to uncover fundamental mechanisms...
5.
Dervyn E, Planson A, Tanaka K, Chubukov V, Guerin C, Derozier S, et al.
Nucleic Acids Res . 2023 Mar; 51(6):2974-2992. PMID: 36919610
Genome-scale engineering enables rational removal of dispensable genes in chassis genomes. Deviating from this approach, we applied greedy accumulation of deletions of large dispensable regions in the Bacillus subtilis genome,...
6.
Bidnenko V, Nicolas P, Guerin C, Derozier S, Chastanet A, Dairou J, et al.
PLoS Genet . 2023 Feb; 19(2):e1010618. PMID: 36735730
Transcription termination factor Rho is known for its ubiquitous role in suppression of pervasive, mostly antisense, transcription. In the model Gram-positive bacterium Bacillus subtilis, de-repression of pervasive transcription by inactivation...
7.
Henriques G, McGovern S, Neef J, Antelo-Varela M, Gotz F, Otto A, et al.
mSphere . 2020 Oct; 5(5). PMID: 33028682
The membrane protease SppA of was first described as a signal peptide peptidase and later shown to confer resistance to lantibiotics. Here, we report that SppA forms octameric complexes with...
8.
Planson A, Sauveplane V, Dervyn E, Jules M
Biochim Biophys Acta Gene Regul Mech . 2020 Feb; 1863(5):194502. PMID: 32044462
Bacteria are sophisticated systems with high capacity and flexibility to adapt to various environmental conditions. Each prokaryote however possesses a defined metabolic network, which sets its overall metabolic capacity, and...
9.
Gauvry E, Mathot A, Couvert O, Leguerinel I, Jules M, Coroller L
Appl Environ Microbiol . 2019 Mar; 85(10). PMID: 30902849
Spore-forming bacteria are natural contaminants of food raw materials, and sporulation can occur in many environments from farm to fork. In order to characterize and to predict spore formation over...
10.
Jules M
Microb Cell . 2018 Jan; 5(1):56-59. PMID: 29354650
Synthetic Biology (SB) aims at the rational design and engineering of novel biological functions and systems. By facilitating the engineering of living organisms, SB promises to facilitate the development of...