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Matthias Steinfath

Explore the profile of Matthias Steinfath including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 1076
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Recent Articles
1.
Diederich K, Steinfath M, Bannach-Brown A, Bert B, Butzke D, Wildner P, et al.
F1000Res . 2025 Jan; 13():858. PMID: 39839731
The translation of animal-based biomedical research into clinical research is often inadequate. Maximizing translation should be central to animal research on human diseases, guiding researchers in study design and animal...
2.
Ohnesorge N, Wilzopolski J, Steinfath M, Lewejohann L, Banneke S, Heinl C
Front Neurosci . 2024 Oct; 18:1456322. PMID: 39381680
Fast and effective anesthesia is the key for refining many invasive procedures in fish and gaining reliable data. For fish as for all vertebrates, it is also required by European...
3.
Scheinpflug J, Hofer C, Schmerbeck S, Steinfath M, Doka J, Tesfahunegn Y, et al.
Lab Chip . 2023 Jul; 23(15):3405-3423. PMID: 37395321
Throughout life, continuous remodelling is part of human bone biology and depends on the simultaneous action of physicochemical parameters such as oxygen tension and varying mechanical load. Thus, suitable model...
4.
Buhler M, Fahrlander J, Sauter A, Becker M, Wistorf E, Steinfath M, et al.
Life Sci Alliance . 2022 Nov; 6(1). PMID: 36384894
The role of the alternate G protein-coupled estrogen receptor 1 (GPER1) in colorectal cancer (CRC) development and progression is unclear, not least because of conflicting clinical and experimental evidence for...
5.
Rudeck J, Vogl S, Heinl C, Steinfath M, Fritzwanker S, Kliewer A, et al.
Pharmacol Biochem Behav . 2020 Feb; 191:172877. PMID: 32088361
Buprenorphine is a commonly used opioid to treat moderate to severe pain in mice. Although strain differences regarding basal pain sensitivity and the analgesic effect of other opioids have been...
6.
Steinfath M, Vogl S, Violet N, Schwarz F, Mielke H, Selhorst T, et al.
PLoS One . 2018 Sep; 13(9):e0202762. PMID: 30208060
We developed a new probabilistic model to assess the impact of recommendations rectifying the reproducibility crisis (by publishing both positive and 'negative' results and increasing statistical power) on competing objectives,...
7.
Bert B, Dorendahl A, Leich N, Vietze J, Steinfath M, Chmielewska J, et al.
PLoS Biol . 2017 Dec; 15(12):e2003217. PMID: 29240762
In the European Union (EU), animal welfare is seen as a matter of great importance. However, with respect to animal experimentation, European citizens feel quite uninformed. The European Directive 2010/63/EU...
8.
Weidner C, Steinfath M, Wistorf E, Oelgeschlager M, Schneider M, Schonfelder G
J Vis Exp . 2017 Sep; (126). PMID: 28872130
Recent studies that compared transcriptomic datasets of human diseases with datasets from mouse models using traditional gene-to-gene comparison techniques resulted in contradictory conclusions regarding the relevance of animal models for...
9.
Weidner C, Steinfath M, Opitz E, Oelgeschlager M, Schonfelder G
EMBO Mol Med . 2016 Jun; 8(8):831-8. PMID: 27311961
The mouse is the main model organism used to study the functions of human genes because most biological processes in the mouse are highly conserved in humans. Recent reports that...
10.
Vogl S, Steinfath M, Lutz W, Schonfelder G
Basic Clin Pharmacol Toxicol . 2015 Dec; 118(6):496-8. PMID: 26617075
No abstract available.