Matthias Schmidt
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Explore the profile of Matthias Schmidt including associated specialties, affiliations and a list of published articles.
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405
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5446
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Recent Articles
11.
Karimi-Farsijani S, Sharma K, Ugrina M, Kuhn L, Pfeiffer P, Haupt C, et al.
Nat Commun
. 2024 Nov;
15(1):9648.
PMID: 39511224
Systemic ALys amyloidosis is a debilitating protein misfolding disease that arises from the formation of amyloid fibrils from C-type lysozyme. We here present a 2.8 Å cryo-electron microscopy structure of...
12.
Hamel C, Avard B, Dea N, Margau R, Mattar A, Michaud A, et al.
Can Assoc Radiol J
. 2024 Oct;
76(2):239-244.
PMID: 39437341
The Canadian Association of Radiologists (CAR) Spine Expert Panel is made up of physicians from the disciplines of radiology, emergency medicine, neurology, neurosurgery, physiatry, a patient advisor, and an epidemiologist/guideline...
13.
Sammuller F, Schmidt M
Phys Rev E
. 2024 Oct;
110(3):L032601.
PMID: 39425325
Recently, Dijkman et al. [arXiv:2403.15007] proposed training classical neural density functionals via bulk pair-correlation matching. We show their method to be an efficient regularizer for neural functionals based on local...
14.
Ibrahim H, Guo M, Hilscher S, Erdmann F, Schmidt M, Schutkowski M, et al.
Bioorg Chem
. 2024 Oct;
153:107887.
PMID: 39423771
Class I HDACs are considered promising targets for cancer due to their role in epigenetic modifications. The main challenges in developing a new, potent and non-toxic class I HDAC inhibitor...
15.
Fischer T, Dietlein F, Bongartz D, Klehr M, Zimmermanns B, Schmidt M, et al.
Int J Mol Sci
. 2024 Oct;
25(19).
PMID: 39409066
Preliminary studies on a radioactive antibody against the neural cell adhesion molecule (NCAM) demonstrated a significant accumulation of [I]I-ERIC1 in neuroblastoma tumor cells in mice. This study aims to validate...
16.
Halilovic M, Abdelsalam M, Zabkiewicz J, Lazenby M, Alvares C, Schmidt M, et al.
Leukemia
. 2024 Sep;
38(12):2561-2572.
PMID: 39300221
Internal tandem duplications in the FMS-like tyrosine kinase-3 (FLT3-ITD) are common mutations in acute myeloid leukemia (AML). Proteolysis-targeting chimeras (PROTACs) that induce proteasomal degradation of mutated FLT3 emerge as innovative...
17.
Berluti F, Baselious F, Hagemann S, Hilscher S, Schmidt M, Huttelmaier S, et al.
Arch Pharm (Weinheim)
. 2024 Sep;
357(11):e2400437.
PMID: 39291901
Class I histone deacetylases (HDACs) are considered promising targets in current cancer research. To obtain subtype-selective and potent HDAC inhibitors, we used the aminobenzamide scaffold as the zinc-binding group and...
18.
Sammuller F, Robitschko S, Hermann S, Schmidt M
Phys Rev Lett
. 2024 Sep;
133(9):098201.
PMID: 39270167
We present a scheme for investigating arbitrary thermal observables in spatially inhomogeneous equilibrium many-body systems. Extending the grand canonical ensemble yields any given observable as an explicit hyperdensity functional. Associated...
19.
Tang F, Tucker L, Nadiveedhi M, Hladun C, Morse J, Ali M, et al.
bioRxiv
. 2024 Sep;
PMID: 39229205
Hypochlorous acid (HOCl) is crucial for pathogen defense, but an imbalance in HOCl levels can lead to tissue damage and inflammation. Existing HOCl indicators employ an oxidation approach, which may...
20.
Morse J, Nadiveedhi M, Schmidt M, Tang F, Hladun C, Ganesh P, et al.
bioRxiv
. 2024 Aug;
PMID: 39149292
Chloride plays a crucial role in various cellular functions, and its level is regulated by a variety of chloride transporters and channels. However, to date, we still lack the capability...