Matthias Sausbier
Overview
Explore the profile of Matthias Sausbier including associated specialties, affiliations and a list of published articles.
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30
Citations
1049
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Recent Articles
1.
Langst N, Adler J, Schweigert O, Kleusberg F, Cruz Santos M, Knauer A, et al.
Int J Mol Sci
. 2021 Sep;
22(18).
PMID: 34576086
The cysteine-rich LIM-only protein 4 (CRP4), a LIM-domain and zinc finger containing adapter protein, has been implicated as a downstream effector of the second messenger 3',5'-cyclic guanosine monophosphate (cGMP) pathway...
2.
Lu R, Lukowski R, Sausbier M, Zhang D, Sisignano M, Schuh C, et al.
Pain
. 2013 Dec;
155(3):556-565.
PMID: 24333777
Large conductance calcium-activated potassium (BKCa) channels are important regulators of neuronal excitability. Although there is electrophysiological evidence for BKCa channel expression in sensory neurons, their in vivo functions in pain...
3.
Oeggerli M, Tian Y, Ruiz C, Wijker B, Sauter G, Obermann E, et al.
PLoS One
. 2012 Aug;
7(8):e41664.
PMID: 22899999
KCNMA1 encodes the α-subunit of the large conductance, voltage and Ca(2+)-activated (BK) potassium channel and has been reported as a target gene of genomic amplification at 10q22 in prostate cancer....
4.
Kurt S, Sausbier M, Ruttiger L, Brandt N, Moeller C, Kindler J, et al.
FASEB J
. 2012 Jun;
26(9):3834-43.
PMID: 22691916
Large conductance, voltage- and Ca(2+)-activated K(+) (BK) channels in inner hair cells (IHCs) of the cochlea are essential for hearing. However, germline deletion of BKα, the pore-forming subunit KCNMA1 of...
5.
Liang Z, Chen L, McClafferty H, Lukowski R, MacGregor D, King J, et al.
J Physiol
. 2011 Nov;
589(Pt 24):5965-86.
PMID: 22041182
The anterior pituitary corticotroph is a major control point for the regulation of the hypothalamic-pituitary-adrenal (HPA) axis and the neuroendocrine response to stress. Although corticotrophs are known to be electrically...
6.
Sausbier U, Dullin C, Missbach-Guentner J, Kabagema C, Flockerzie K, Kuscher G, et al.
PLoS One
. 2011 Jun;
6(6):e21168.
PMID: 21695131
Background: The process of bone resorption by osteoclasts is regulated by Cathepsin K, the lysosomal collagenase responsible for the degradation of the organic bone matrix during bone remodeling. Recently, Cathepsin...
7.
Liao Y, Kristiansen A, Oksvold C, Tuvnes F, Gu N, Runden-Pran E, et al.
PLoS One
. 2011 Jan;
5(12):e15601.
PMID: 21209897
Neuronal calcium-activated potassium channels of the BK type are activated by membrane depolarization and intracellular Ca(2+) ions. It has been suggested that these channels may play a key neuroprotective role...
8.
Foller M, Bobbala D, Koka S, Boini K, Mahmud H, Kasinathan R, et al.
Pflugers Arch
. 2010 Sep;
460(6):1029-44.
PMID: 20857305
Increased cytosolic Ca(2+) concentrations activate Gardos K(+) channels in human erythrocytes with membrane hyperpolarization, efflux of K(+), Cl⁻, and osmotically obliged H₂O resulting in cell shrinkage, a phenomenon referred to...
9.
Chen X, Kovalchuk Y, Adelsberger H, Henning H, Sausbier M, Wietzorrek G, et al.
Proc Natl Acad Sci U S A
. 2010 Jun;
107(27):12323-8.
PMID: 20566869
The large-conductance voltage- and calcium-activated potassium (BK) channels are ubiquitously expressed in the brain and play an important role in the regulation of neuronal excitation. Previous work has shown that...
10.
Zhou X, Wulfsen I, Utku E, Sausbier U, Sausbier M, Wieland T, et al.
Proc Natl Acad Sci U S A
. 2010 Apr;
107(17):8005-10.
PMID: 20385812
Large conductance voltage- and Ca(2+)-activated potassium channels (BK channels) are important feedback regulators in excitable cells and are potently regulated by protein kinases. The present study reveals a dual role...